1-Propanone, 1-(4-methyl-2-(methylthio)-5-thiazolyl)-3-(4-(2-pyridinyl)-1-piperazinyl)-, dihydrochloride

Modify Date: 2025-10-13 06:11:24

1-Propanone, 1-(4-methyl-2-(methylthio)-5-thiazolyl)-3-(4-(2-pyridinyl)-1-piperazinyl)-, dihydrochloride structure	Common Name	1-Propanone, 1-(4-methyl-2-(methylthio)-5-thiazolyl)-3-(4-(2-pyridinyl)-1-piperazinyl)-, dihydrochloride
	CAS Number	75449-08-0	Molecular Weight	398.97400
	Density	1.3g/cm3	Boiling Point	568.5ºC at 760 mmHg
	Molecular Formula	C₁₇H₂₃ClN₄OS₂	Melting Point	N/A
	MSDS	N/A	Flash Point	297.6ºC

Name	1-(4-methyl-2-methylsulfanyl-1,3-thiazol-5-yl)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-1-one
Synonym	More Synonyms

Density	1.3g/cm3
Boiling Point	568.5ºC at 760 mmHg
Molecular Formula	C₁₇H₂₃ClN₄OS₂
Molecular Weight	398.97400
Flash Point	297.6ºC
Exact Mass	398.10000
PSA	102.87000
LogP	3.76830
Index of Refraction	1.646
InChIKey	LHJYXTUZJFKOLD-UHFFFAOYSA-N
SMILES	CSc1nc(C)c(C(=O)CCN2CCN(c3ccccn3)CC2)s1.Cl

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UC3081300

CHEMICAL NAME :: 1-Propanone, 1-(4-methyl-2-(methylthio)-5-thiazolyl)-3-(4-(2-pyrid inyl)-1-piperazinyl)-, dihydrochloride

CAS REGISTRY NUMBER :: 75449-08-0

LAST UPDATED :: 198712

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C17-H22-N4-O-S2.2Cl-H

MOLECULAR WEIGHT :: 435.47

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 250 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - ptosis Behavioral - changes in motor activity (specific assay)

REFERENCE :: APPHAX Acta Poloniae Pharmaceutica. For English translation, see APPFAR. (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland) V.1- 1937- Volume(issue)/page/year: 36,545,1979

1-(4-Methyl-2-(methylthio)-1,3-thiazol-5-yl)-3-(4-(2-pyridinyl)-1-piperazinyl)-1-propanone

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.