3-HYDRAZINO-6-(2-THIENYL)PYRIDAZINE

Modify Date: 2025-08-28 21:37:24

3-HYDRAZINO-6-(2-THIENYL)PYRIDAZINE Structure
3-HYDRAZINO-6-(2-THIENYL)PYRIDAZINE structure
Common Name 3-HYDRAZINO-6-(2-THIENYL)PYRIDAZINE
CAS Number 75792-87-9 Molecular Weight 192.24100
Density 1.4g/cm3 Boiling Point 466.8ºC at 760 mmHg
Molecular Formula C8H8N4S Melting Point N/A
MSDS N/A Flash Point 236.1ºC

 Names

Name (6-thiophen-2-ylpyridazin-3-yl)hydrazine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4g/cm3
Boiling Point 466.8ºC at 760 mmHg
Molecular Formula C8H8N4S
Molecular Weight 192.24100
Flash Point 236.1ºC
Exact Mass 192.04700
PSA 92.07000
LogP 2.26400
Index of Refraction 1.714
InChIKey ARNOKZCUVMCJQP-UHFFFAOYSA-N
SMILES NNc1ccc(-c2cccs2)nn1

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UR6048000
CHEMICAL NAME :
Pyridazine, 3-hydrazino-6-(2-thienyl)-
CAS REGISTRY NUMBER :
75792-87-9
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C8-H8-N4-S
MOLECULAR WEIGHT :
192.26
WISWESSER LINE NOTATION :
T6NNJ CMZ F- BT5SJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
100 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - changes in motor activity (specific assay) Behavioral - antipsychotic
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,59,1981

 Safety Information

HS Code 2934999090

 Synthetic Route

~84%

3-HYDRAZINO-6-(2-THIENYL)PYRIDAZINE Structure

3-HYDRAZINO-6-(...

CAS#:75792-87-9

Literature: Steiner; Gries; Lenke Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 59 - 63

~%

3-HYDRAZINO-6-(2-THIENYL)PYRIDAZINE Structure

3-HYDRAZINO-6-(...

CAS#:75792-87-9

Literature: Wermuth, Camille-Georges; Bourguignon, Jean-Jacques; Schlewer, Gilbert; Gies, Jean-Pierre; Schoenfelder, Angele; et al. Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 239 - 249

~%

3-HYDRAZINO-6-(2-THIENYL)PYRIDAZINE Structure

3-HYDRAZINO-6-(...

CAS#:75792-87-9

Literature: Steiner; Gries; Lenke Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 59 - 63

~%

3-HYDRAZINO-6-(2-THIENYL)PYRIDAZINE Structure

3-HYDRAZINO-6-(...

CAS#:75792-87-9

Literature: Steiner; Gries; Lenke Journal of Medicinal Chemistry, 1981 , vol. 24, # 1 p. 59 - 63

 Customs

HS Code 2934999090
Summary 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 3-HYDRAZINO-6-(2-THIENYL)PYRIDAZINEBioassay

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Name: Relative potency of compound was measured in conscious SH rats after po administratio...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL790540
Name: Hypotensive activity was measured as ED20 which is the dose lowered the normal arteri...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL781587
Name: Acute toxicity was measured as LD50 in mice after ip administration
Source: ChEMBL
Target: Mus musculus
External Id: CHEMBL740242
Name: Relative potency of compound was measured in anesthetized rats after ip administratio...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL790532
Name: Antihypertensive activity was measured as ED20 which is the dose lowered the normal a...
Source: ChEMBL
Target: Rattus norvegicus
External Id: CHEMBL776977
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1

 Synonyms

6-(2-thienyl)pyridazine-3-ylhydrazine
3-Hydrazino-6-(2-thienyl)pyridazine
3-hydrazinyl-6-(thiophen-2-yl)pyridazine
Pyridazine,3-hydrazino-6-(2-thienyl)
3-hydrazino-6-thien-2-ylpyridazine
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