FA-Ala-Arg-OH

Modify Date: 2024-01-03 12:37:06

FA-Ala-Arg-OH Structure
FA-Ala-Arg-OH structure
Common Name FA-Ala-Arg-OH
CAS Number 76079-06-6 Molecular Weight 365.38
Density 1.38g/cm3 Boiling Point N/A
Molecular Formula C16H23N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of FA-Ala-Arg-OH


FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells[1].

 Names

Name (2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(E)-3-(furan-2-yl)prop-2-enoyl]amino]propanoyl]amino]pentanoic acid
Synonym More Synonyms

 FA-Ala-Arg-OH Biological Activity

Description FA-Ala-Arg is a dipeptide with furylacryloyl group. FA-Ala-Arg breaks down to produce arginine. While cell-surface Carboxypeptidase-D (CPD) also increases intracellular Arg, which is converted to nitric oxide (NO). FA-Ala-Arg enhances NO production in MCF-7 cells. FA-Ala-Arg also increases the cell survival of prolactin (PRL)-treated cells, PRL regulates CPD mRNA levels in cells[1].
Related Catalog
References

[1]. Abdelmagid SA, et al. Prolactin and estrogen up-regulate carboxypeptidase-d to promote nitric oxide production and survival of mcf-7 breast cancer cells. Endocrinology. 2008 Oct;149(10):4821-8.  

 Chemical & Physical Properties

Density 1.38g/cm3
Molecular Formula C16H23N5O5
Molecular Weight 365.38
Exact Mass 365.17000
PSA 177.52000
LogP 2.50170
Index of Refraction 1.608
Storage condition -15°C

 Synonyms

L-Arginine,N(2)-(N-(3-(2-furanyl)-1-oxo-2-propenyl)-L-alanyl)
FA-Ala-arg
Furylacryloylalanylarginine
(2S)-5-(diaminomethylideneamino)-2-[[(2S)-2-[[(E)-3-furan-2-ylprop-2-enoyl]amino]propanoyl]amino]pentanoic acid
Furylacryloyl-ala-arg