Fluzinamide
Modify Date: 2024-01-09 16:49:56
Fluzinamide structure
|
Common Name | Fluzinamide | ||
|---|---|---|---|---|
| CAS Number | 76263-13-3 | Molecular Weight | 274.23900 | |
| Density | 1.337g/cm3 | Boiling Point | 415.7ºC at 760 mmHg | |
| Molecular Formula | C12H13F3N2O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 205.2ºC | |
Use of FluzinamideFluzinamide is an effective antiepileptic. |
| Name | N-methyl-3-[3-(trifluoromethyl)phenoxy]azetidine-1-carboxamide |
|---|---|
| Synonym | More Synonyms |
| Description | Fluzinamide is an effective antiepileptic. |
|---|---|
| Related Catalog | |
| In Vivo | Fluzinamide, an antiepileptic agent effective against partial seizures, is metabolized extensively in mice, rats and dogs[1].The anticonvulsant properties of Fluzinamide (AHR-8559) are evaluated in the kindled amygdaloid seizure model in rats. Fluzinamide significantly attenuates afterdischarge durations and the severity of the accompanying convulsive responses in previously kindled rats at doses that does not cause sedation or ataxia. After acute intraperitoneal injections, the maximum anticonvulsant effectiveness against suprathreshold (400 μA) stimulation is seen at 30 min. Fluzinamide (10-80 mg/kg i.p.) is also evaluated in kindled rats using threshold (20 μA increments) seizures. Low doses of Fluzinamide significantly elevate seizure threshold and reduce both elicited after discharge durations and seizure severity. When administered daily during kindling acquisition, Fluzinamide (20 and 40 mg/kg i.p.) significantly increases the number of trials necessary to complete kindling. The duration and the severity of the responses induced by stimulations during the acquisition period are reduced[2]. |
| References |
| Density | 1.337g/cm3 |
|---|---|
| Boiling Point | 415.7ºC at 760 mmHg |
| Molecular Formula | C12H13F3N2O2 |
| Molecular Weight | 274.23900 |
| Flash Point | 205.2ºC |
| Exact Mass | 274.09300 |
| PSA | 45.06000 |
| LogP | 2.25010 |
| Index of Refraction | 1.511 |
| Storage condition | 2-8℃ |
| 1-Azetidinecarboxamide,N-methyl-3-(3-(trifluoromethyl)phenoxy) |
| Fluzinamida [Spanish] |
| Fluzinamidum [Latin] |
| Fluzinamidum |
| FLUZINAMIDE |
| Fluzinamida |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Fluzinamide
- Price: Negotiable
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Huang
- Email: sales@echemcloud.com
- DC Chemicals Limited
- China
- Product Name: Fluzinamide
- Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: Fluzinamide
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
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Price: $480/1mg
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