Lavoltidine
Modify Date: 2025-08-25 17:28:34
Lavoltidine structure
|
Common Name | Lavoltidine | ||
|---|---|---|---|---|
| CAS Number | 76956-02-0 | Molecular Weight | 359.46600 | |
| Density | 1.23g/cm3 | Boiling Point | 566.9ºC at 760 mmHg | |
| Molecular Formula | C19H29N5O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 296.6ºC | |
Use of LavoltidineLavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia[1]. |
| Name | loxtidine |
|---|---|
| Synonym | More Synonyms |
| Description | Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia[1]. |
|---|---|
| Related Catalog | |
| Target |
H2 Receptor |
| In Vivo | Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice[1]. Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice[1]. Animal Model: Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis[1] Dosage: 0.5 g/L Administration: Orally (drinking water); changed weekly; for 3 months Result: Showed partial suppression of both gastric acid secretion and progression to neoplasia. |
| References |
| Density | 1.23g/cm3 |
|---|---|
| Boiling Point | 566.9ºC at 760 mmHg |
| Molecular Formula | C19H29N5O2 |
| Molecular Weight | 359.46600 |
| Flash Point | 296.6ºC |
| Exact Mass | 359.23200 |
| PSA | 75.44000 |
| LogP | 2.18520 |
| Index of Refraction | 1.614 |
| InChIKey | VTLNPNNUIJHJQB-UHFFFAOYSA-N |
| SMILES | Cn1nc(CO)nc1NCCCOc1cccc(CN2CCCCC2)c1 |
| LAVOLTIDINE |
| Lavoltidina |
| Lavoltidinum |
| [1-methyl-5-[3-[3-(piperidin-1-ylmethyl)phenoxy]propylamino]-1,2,4-triazol-3-yl]methanol |
| Loxtidinum |
| Loxtidina |
| Loxtidine |
| Lavoltidinum [INN-Latin] |
| Loxtidinum [Latin] |
| Lavoltidine [INN:BAN] |
| Loxtidina [Spanish] |