Thymosin beta 4 acetate

Modify Date: 2024-01-02 13:53:40

Thymosin beta 4 acetate structure	Common Name	Thymosin beta 4 acetate
	CAS Number	77591-33-4	Molecular Weight	4963.44000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁₂H₃₅₀N₅₆O₇₈S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Thymosin beta 4 acetate

Thymosin beta 4 is a potent regulator of actin polymerization in living cells. Sequence: Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser.

Name	Thymosin beta 4 acetate
Synonym	More Synonyms

Description	Thymosin beta 4 is a potent regulator of actin polymerization in living cells. Sequence: Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser.
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Cardiovascular Disease Peptides
Target	Actin[1].
In Vitro	As indicated by the significant reduction in the binding offluorescent phalloidin to injected cells, it is clear that (Thymosin beta 4 can induce an extensive depolymerization of actin filaments[1]. Treatment with the exogenous Thymosin beta 4 peptide inhibits the proliferation and migration of activated HSCs and reduces liver fibrosis[2].
References	[1]. Sanders MC, et al. Thymosin beta 4 (Fx peptide) is a potent regulator of actin polymerization in living cells. Proc Natl Acad Sci U S A. 1992 May 15;89(10):4678-82. [2]. Kim J et al. Thymosin Beta 4 Is a Potential Regulator of Hepatic Stellate Cells. Vitam Horm. 2016;102:121-49.