Piperazine, 1,4-bis[ (2, 3-dihydro-1,4-benzodioxin-2-yl)methyl]-

Modify Date: 2024-04-01 17:31:38

Piperazine, 1,4-bis[ (2, 3-dihydro-1,4-benzodioxin-2-yl)methyl]- structure	Common Name	Piperazine, 1,4-bis[ (2, 3-dihydro-1,4-benzodioxin-2-yl)methyl]-
	CAS Number	7762-32-5	Molecular Weight	382.45300
	Density	1.223g/cm3	Boiling Point	513.6ºC at 760 mmHg
	Molecular Formula	C₂₂H₂₆N₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	147ºC

Name	Piperazine, 1,4-bis[ (2, 3-dihydro-1,4-benzodioxin-2-yl)methyl]
Synonym	More Synonyms

Density	1.223g/cm3
Boiling Point	513.6ºC at 760 mmHg
Molecular Formula	C₂₂H₂₆N₂O₄
Molecular Weight	382.45300
Flash Point	147ºC
Exact Mass	382.18900
PSA	43.40000
LogP	2.15980
Index of Refraction	1.586

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TK8750000

CHEMICAL NAME :: Piperazine, 1,4-bis(1,4-benzodioxan-2-ylmethyl)-

CAS REGISTRY NUMBER :: 7762-32-5

LAST UPDATED :: 199012

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C22-H26-N2-O4

MOLECULAR WEIGHT :: 382.50

WISWESSER LINE NOTATION :: T66 BO EOJ C1- AT6N DNTJ D1- CT66 BO EOJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMPCAS Journal of Medicinal and Pharmaceutical Chemistry. (Washington, DC) V.1-5, 1959-62. For publisher information, see JMCMAR. Volume(issue)/page/year: 5,1285,1962

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 12,355,1953

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 43 mg/kg

TOXIC EFFECTS :: Behavioral - muscle weakness Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :: FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 12,355,1953

(+)-1,4-bis-(2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-piperazine

1,4-Bis[(2,3-dihydro-1,4-benzodioxin-2-yl)methyl]piperazine

dibozane

Dibozan

MCN-181