p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside

Modify Date: 2024-03-03 18:26:45

p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside Structure
p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside structure
Common Name p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside
CAS Number 77640-21-2 Molecular Weight 447.39100
Density N/A Boiling Point N/A
Molecular Formula C18H25NO12 Melting Point 233-236ºC dec.
MSDS N/A Flash Point N/A

 Use of p-Nitrophenyl 2-O-(b-L-Fucopyranosyl)-b-D-galactopyranoside


4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside is a synthetic chromogenic substrate and can be used in the assay of α-fucosidases which hydrolyze the glycosidic linkage Fuc α1-2Gal. The assay is based on the sequential action of α-fucosidase and an exogenously added exo-β-d-galactosidase to release the easily measurable p-nitrophenol moiety[1].

 Names

Name (2R,3S,4R,5S,6S)-2-[(2S,3R,4S,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-(4-nitrophenoxy)oxan-3-yl]oxy-6-methyloxane-3,4,5-triol
Synonym More Synonyms

  Biological Activity

Description 4-Nitrophenyl 2-O-(β-L-Fucopyranosyl)-β-D-Galactopyranoside is a synthetic chromogenic substrate and can be used in the assay of α-fucosidases which hydrolyze the glycosidic linkage Fuc α1-2Gal. The assay is based on the sequential action of α-fucosidase and an exogenously added exo-β-d-galactosidase to release the easily measurable p-nitrophenol moiety[1].
Related Catalog
References

[1]. R A DiCioccio, et al. Synthesis and use of p-nitrophenyl-2-O-(alpha-L-fucopyranosyl)-beta-D-galactopyranoside for the rapid detection of substrate-specific alpha-L-fucosidases. Anal Biochem. 1981 Feb;111(1):176-83.

 Chemical & Physical Properties

Melting Point 233-236ºC dec.
Molecular Formula C18H25NO12
Molecular Weight 447.39100
Exact Mass 447.13800
PSA 204.12000

 Synonyms

p-Nitrophenyl 2-O-(|A-L-fucopyranosyl)-|A-D-galactopyranoside
W0352
4-Nitrophenyl 2-O-(6-Deoxy-|A-L-galactopyranosyl)-|A-D-galactopyranoside
Fuc1-|A-2Gal-|A-PNP