Scaff10-8

Modify Date: 2024-04-02 21:53:30

Scaff10-8 Structure
Scaff10-8 structure
Common Name Scaff10-8
CAS Number 777857-56-4 Molecular Weight 378.37
Density N/A Boiling Point N/A
Molecular Formula C22H18O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Scaff10-8


Scaff10-8 is an inhibitor of AKAP-Lbc-RhoA interaction that acts by promoting the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.

 Names

Name Scaff10-8

 Scaff10-8 Biological Activity

Description Scaff10-8 is an inhibitor of AKAP-Lbc-RhoA interaction that acts by promoting the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells.
References 1. Schrade K, Tröger J, Eldahshan A, Zühlke K, Abdul Azeez KR, Elkins JM, Neuenschwander M, Oder A, Elkewedi M, Jaksch S, Andrae K, Li J, Fernandes J, Müller PM, Grunwald S, Marino SF, Vukićević T, Eichhorst J, Wiesner B, Weber M, Kapiloff M, Rocks O, Daumke O, Wieland T, Knapp S, von Kries JP, Klussmann E. An AKAP-Lbc-RhoA interaction inhibitor promotes the translocation of aquaporin-2 to the plasma membrane of renal collecting duct principal cells. PLoS One. 2018 Jan 26;13(1):e0191423. doi: 10.1371/journal.pone.0191423. eCollection 2018. PubMed PMID: 29373579; PubMed Central PMCID: PMC5786306.

 Chemical & Physical Properties

Molecular Formula C22H18O6
Molecular Weight 378.37