Velaresol

Modify Date: 2024-02-04 21:30:38

Velaresol Structure
Velaresol structure
Common Name Velaresol
CAS Number 77858-21-0 Molecular Weight 238.24
Density 1.293g/cm3 Boiling Point 452.3ºC at 760 mmHg
Molecular Formula C12H14O5 Melting Point N/A
MSDS N/A Flash Point 176.1ºC

 Use of Velaresol


Velaresol (BW 12C) is a potent left-shifting anti-sickling compound in vitro[1]. Sickle cell disease is an inherited disorder of the hemoglobin molecule. When hemoglobin molecules are exposed to a variety of environments, the red blood cell hemoglobin polymerizes, twists, and morphs into a sickle shape.

 Names

Name 5-(2-Formyl-3-hydroxyphenoxy)pentanoic acid
Synonym More Synonyms

 Velaresol Biological Activity

Description Velaresol (BW 12C) is a potent left-shifting anti-sickling compound in vitro[1]. Sickle cell disease is an inherited disorder of the hemoglobin molecule. When hemoglobin molecules are exposed to a variety of environments, the red blood cell hemoglobin polymerizes, twists, and morphs into a sickle shape.
Related Catalog
References

[1]. Fitzharris P, et al. The effects in volunteers of BW12C, a compound designed to left-shift the blood-oxygen saturation curve. Br J Clin Pharmacol. 1985 Apr;19(4):471-81.  

 Chemical & Physical Properties

Density 1.293g/cm3
Boiling Point 452.3ºC at 760 mmHg
Molecular Formula C12H14O5
Molecular Weight 238.24
Flash Point 176.1ºC
Exact Mass 238.08400
PSA 83.83000
LogP 1.83840
Index of Refraction 1.584
Storage condition -20℃

 Safety Information

HS Code 2918990090

 Synthetic Route

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Velaresol Structure

Velaresol

CAS#:77858-21-0

Literature: Burroughts Wellcome Co. Patent: US4410537 A1, 1983 ;

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Velaresol Structure

Velaresol

CAS#:77858-21-0

Literature: Burroughts Wellcome Co. Patent: US4410537 A1, 1983 ;

 Customs

HS Code 2918990090
Summary 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

BW 12C
Velaresol
12C79
5-(2-Formyl-3-hydroxyphenoxy)valeric acid
EINECS 278-778-8
2-4'-carboxybutoxy-6-hydroxybenzaldehyde
12C
Pentanoic acid,5-(2-formyl-3-hydroxyphenoxy)