Droxicainide

Modify Date: 2024-01-11 18:00:02

Droxicainide Structure
Droxicainide structure
Common Name Droxicainide
CAS Number 78289-26-6 Molecular Weight 276.37400
Density 1.133g/cm3 Boiling Point 456.2ºC at 760 mmHg
Molecular Formula C16H24N2O2 Melting Point N/A
MSDS N/A Flash Point 229.7ºC

 Use of Droxicainide


Droxicainide is an antiarrhythmic agent.

 Names

Name N-(2,6-dimethylphenyl)-1-(2-hydroxyethyl)piperidine-2-carboxamide
Synonym More Synonyms

 Droxicainide Biological Activity

Description Droxicainide is an antiarrhythmic agent.
Related Catalog
In Vivo In coronary artery occlusion study, Droxicainide reduces hypoperfused area that evolves to necrosis, and reduces the infarct size in dogs[1]. Droxicainide decreases the sinus node, atrial and ventricular excitability and contractile force and increases the refractoriness in the study of spontaneously beating atria, electrically stimulated atria and papillary muscles isolated from rats[2].
References

[1]. Faria DB, et al. Effects of lidocaine and droxicainide on myocardial necrosis: a comparative study. J Am Coll Cardiol. 1983 Jun;1(6):1447-52.

[2]. Helgesen KG, et al. Comparison of electrophysiological and mechanical effects of droxicainide and lidocaine on heart muscle isolated from rats. Acta Pharmacol Toxicol (Copenh). 1984 Oct;55(4):303-7.

 Chemical & Physical Properties

Density 1.133g/cm3
Boiling Point 456.2ºC at 760 mmHg
Molecular Formula C16H24N2O2
Molecular Weight 276.37400
Flash Point 229.7ºC
Exact Mass 276.18400
PSA 56.06000
LogP 2.67610
Index of Refraction 1.578
Storage condition 2-8℃

 Synonyms

als-1249
unii-j6w196lmv3
Droxicainide
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