Pirsue

Modify Date: 2024-01-07 09:13:09

Pirsue Structure
Pirsue structure
Common Name Pirsue
CAS Number 78822-40-9 Molecular Weight 465.433
Density N/A Boiling Point N/A
Molecular Formula C17H32Cl2N2O5S Melting Point >160 °C (dec.) (lit.)
MSDS N/A Flash Point N/A

 Use of Pirsue


Pirlimycin (RU 38882) hydrochloride, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin hydrochloride acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome[1].

 Names

Name pirlimycin hydrochloride
Synonym More Synonyms

 Pirsue Biological Activity

Description Pirlimycin (RU 38882) hydrochloride, a lincosamide antibiotic, is active against Gram-positive bacteria. Pirlimycin hydrochloride acts by inhibiting bacterial protein synthesis via binding with the 50S subunit of the ribosome[1].
Related Catalog
References

[1]. Birkenmeyer RD, et, al. Synthesis and antimicrobial activity of clindamycin analogues: pirlimycin, 1,2 a potent antibacterial agent. J Med Chem. 1984 Feb;27(2):216-23.  

 Chemical & Physical Properties

Melting Point >160 °C (dec.) (lit.)
Molecular Formula C17H32Cl2N2O5S
Molecular Weight 465.433
Exact Mass 464.151459
PSA 136.35000
LogP 1.56900

 Synonyms

Methyl (5R)-5-[(1S,2S)-2-chloro-1-({[(2S,4R)-4-ethyl-2-piperidinyl]carbonyl}amino)propyl]-1-thio-β-L-arabinopyranoside hydrochloride hydrate
Methyl (2S-cis)-7-Chloro-6,7,8-trideoxy-6-(((4-ethyl-2-piperidinyl)carbonyl)amino)-1-thio-L-threo-a-D-galacto-octopyranoside Monohydrochloride
Methyl 7-chloro-6,7,8-trideoxy-6-({[(2S,4R)-4-ethylpiperidin-2-yl]carbonyl}amino)-1-thio-L-threo-α-D-galacto-octopyranoside hydrochloride hydrate
pirlimycin hydrochloride, antibiotic for culture media use only
pirlimycin
L-threo-α-D-galacto-Octopyranoside, methyl 7-chloro-6,7,8-trideoxy-6-[[[(2S,4R)-4-ethyl-2-piperidinyl]carbonyl]amino]-1-thio-, hydrochloride, hydrate (1:1:1)
Pirsue
U 57903E