PBD-150
Modify Date: 2024-01-09 08:23:39
PBD-150 structure
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Common Name | PBD-150 | ||
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| CAS Number | 790663-33-1 | Molecular Weight | 320.411 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H20N4O2S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PBD-150A potent glutaminyl cyclase (QC) inhibitor with Ki of 60 nM; significantly reduces depositions of Aβ3(pGlu)-40/42 in brain in transgenic mouse models and Drosophila model of Alzheimer diseas. |
| Name | PBD-150 |
|---|
| Description | A potent glutaminyl cyclase (QC) inhibitor with Ki of 60 nM; significantly reduces depositions of Aβ3(pGlu)-40/42 in brain in transgenic mouse models and Drosophila model of Alzheimer diseas. |
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| Related Catalog | |
| In Vivo | PBD-150 is able to reduce the deposition of pyroglutamate-modified amyloid-β peptides in brain of transgenic mouse models of Alzheimer disease, leading to a significant improvement of learning and memory in those transgenic animals[3]. |
| References |
| Molecular Formula | C15H20N4O2S |
|---|---|
| Molecular Weight | 320.411 |