S-(-)-Warfarin-d5

Modify Date: 2024-07-09 20:00:14

S-(-)-Warfarin-d5 structure	Common Name	S-(-)-Warfarin-d5
	CAS Number	791013-22-4	Molecular Weight	313.36
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₁D₅O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of S-(-)-Warfarin-d5

S-(-)-Warfarin-d5 is deuterium labeled S-(-)-Warfarin. S-(-)-Warfarin is a more potent enantiomer of Warfarin as a vitamin K antagonist with anticoagulant effect[1].

Name	4-Hydroxy-3-[(1S)-3-oxo-1-(2H5)phenylbutyl]-2H-chromen-2-one

Description	S-(-)-Warfarin-d5 is deuterium labeled S-(-)-Warfarin. S-(-)-Warfarin is a more potent enantiomer of Warfarin as a vitamin K antagonist with anticoagulant effect[1].
Related Catalog	Research Areas >> Others Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Bai J, et al. Metabolic profiling of HepG2 cells incubated with S(-) and R(+) enantiomers of anti-coagulating drug warfarin. Metabolomics. 2011 Sep;7(3):353-362.

Molecular Formula	C₁₉H₁₁D₅O₄
Molecular Weight	313.36
Exact Mass	313.13600
PSA	67.51000
LogP	3.60960