Calcium Levofolinate
Modify Date: 2025-08-24 12:37:48
Calcium Levofolinate structure
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Common Name | Calcium Levofolinate | ||
|---|---|---|---|---|
| CAS Number | 80433-71-2 | Molecular Weight | 511.501 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H21CaN7O7 | Melting Point | 240-250ºC | |
| MSDS | N/A | Flash Point | N/A | |
Use of Calcium LevofolinateLevoleucovorin calcium is the calcium salt of Levoleucovorin, which is the enantiomerically active form of folinic acid.IC50 value: Target: Levoleucovorin is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer. Levoleucovorin is also used in combination chemotherapy with fluorouracil (5-FU) to treat colorectal cancer that has spread to other parts of the body. This medicine only treats the symptoms of colorectal cancer and does not treat the cancer itself. |
| Name | calcium,(2S)-2-[[4-[[(6S)-2-amino-5-formyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate |
|---|---|
| Synonym | More Synonyms |
| Description | Levoleucovorin calcium is the calcium salt of Levoleucovorin, which is the enantiomerically active form of folinic acid.IC50 value: Target: Levoleucovorin is used to treat or prevent toxic effects of methotrexate in people who have received methotrexate to treat bone cancer. Levoleucovorin is also used in combination chemotherapy with fluorouracil (5-FU) to treat colorectal cancer that has spread to other parts of the body. This medicine only treats the symptoms of colorectal cancer and does not treat the cancer itself. |
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| Related Catalog | |
| References |
[1]. Levomefolic acid. From Wikipedia, the free encyclopedia |
| Melting Point | 240-250ºC |
|---|---|
| Molecular Formula | C20H21CaN7O7 |
| Molecular Weight | 511.501 |
| Exact Mass | 511.112823 |
| PSA | 225.50000 |
| InChIKey | KVUAALJSMIVURS-NQJMHYHOSA-L |
| SMILES | Nc1nc2c(c(=O)[nH]1)N(C=O)C(CNc1ccc(C(=O)NC(CCC(=O)[O-])C(=O)[O-])cc1)CN2.[Ca+2] |
| Storage condition | -20°C |
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Name: Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VER...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL4513082
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Name: Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Cac...
Source: ChEMBL
Target: Severe acute respiratory syndrome coronavirus 2
External Id: CHEMBL4303805
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|
Name: SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response f...
Source: ChEMBL
Target: Replicase polyprotein 1ab
External Id: CHEMBL4495582
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1
| folinic acid calcium salt |
| Levoleucovorin calcium (USAN) |
| Calcium (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydro-6-pteridinyl]methyl}amino)benzoyl]amino}pentanedioate |
| calcium levofolinate |
| Fusilev (TN) |
| Calcium N-(p-((((6S)-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamate (1:1) |
| Isovorin |
| 778XL6VBS8 |
| Calcium 2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate |
| Levofolinate calcium (JAN) |
| Elvorine |
| Levoleucovorin (Calcium) |
| Calcium (2S)-2-{[4-({[(6S)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]amino}pentanedioate |
| LEVOLEUCOVORIN CALCIUM |
| N-[4-[[[(6S)-2-Amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-L-glutamic Acid Calcium Salt (1:1) |
| L-Glutamic acid, N-[4-[[[(6S)-2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl]methyl]amino]benzoyl]-, calcium salt (1:1) |
| UNII-778XL6VBS8 |
| Isovorin (TN) |
| Calcium levofolinate (INN) |
| MFCD00865527 |
| Levofolinate |