Desmetramadol
Desmetramadol structure
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Common Name | Desmetramadol | ||
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| CAS Number | 80456-81-1 | Molecular Weight | 285.81000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H24ClNO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of DesmetramadolDesmetramadol is a central analgesic drug candidate. Desmetramadol inhibits 5-hydroxytryptamine type 2C receptors expressed in Xenopus Oocytes. |
| Name | o-desmethyl tramadol hcl |
|---|---|
| Synonym | More Synonyms |
| Molecular Formula | C15H24ClNO2 |
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| Molecular Weight | 285.81000 |
| Exact Mass | 285.15000 |
| PSA | 43.70000 |
| LogP | 3.13360 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Simultaneous Determination of Tramadol and Its Metabolite in Human Urine by the Gas Chromatography-Mass Spectrometry Method.
J. Chromatogr. Sci. 53 , 1037-43, (2015) A sensitive and efficient method was developed for determination of tramadol and its metabolite (O-desmethyltramadol) in human urine by gas chromatography-mass spectrometry. Tramadol, O-desmethyltrama... |
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Pharmacokinetics of tramadol and o-desmethyltramadol in goats after intravenous and oral administration.
J. Vet. Pharmacol. Ther. 31(1) , 45-51, (2008) The aim of this trial was to implement a method to obtain a tool for analyses of tramadol and the main metabolite, o-desmethyltramadol (M1), in goat's plasma, and to evaluate the pharmacokinetics of t... |
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The enantiomers of tramadol and its major metabolite inhibit peristalsis in the guinea pig small intestine via differential mechanisms.
BMC Pharmacol. 7 , 5, (2007) Inhibition of intestinal peristalsis is a major side effect of opioid analgesics. Although tramadol is an opioid-like analgesic, its effect on gut motility is little known. Therefore, the effect of (+... |
| Desmethyltramadol,O |
| O-demethly tramadol |
| Phenol,m-(2-(dimethylaminomethyl)-1-hydroxycyclohexyl) |
| (+/-)-2(e)-Dimethylaminomethyl-1(e)-(3-methoxyphenyl)-cyclohexan-1-ol |
| O-Demethyltramadol |
| Cyclohexanol,1-(m-hydroxyphenyl)-2-(dimethylaminomethyl) |
| m-(2-(Dimethylaminomethyl)-1-hydroxycyclohexyl)phenol |
| 3-[(1-RS,2-RS)-2-[(dimethylamino)methyl]-1-hydroxycyclohexyl]-phenol |
| O-desmethyl-cis-tramadol |