TRV056 structure
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Common Name | TRV056 | ||
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CAS Number | 812644-79-4 | Molecular Weight | 1103.23 | |
Density | N/A | Boiling Point | N/A | |
Molecular Formula | C52H74N14O13 | Melting Point | N/A | |
MSDS | N/A | Flash Point | N/A |
Use of TRV056TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV056 is efficacious in stimulating cellular Gq-mediated signaling. TRV056 can be used to develop the Gq-biased AT1R agonists[1]. |
Name | TRV056 |
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Description | TRV056 is a Gq-biased ligand of the angiotensin II receptor type 1 (AT1R). TRV056 is efficacious in stimulating cellular Gq-mediated signaling. TRV056 can be used to develop the Gq-biased AT1R agonists[1]. |
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Related Catalog | |
In Vitro | TRV056 is a “gain-of-function” ligand that have >10-fold greater allosteric coupling to Gq than AngII and is also more efficacious in stimulating cellular Gq-mediated signaling (e.g., IP1 generation). Compared to the endogenous ligand angiotensin II (AngII), “Gq-biased” AT1R agonists are more efficacious in stimulating Gq-mediated cellular signaling and in allosterically promoting Gq coupling[1]. |
References |
Molecular Formula | C52H74N14O13 |
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Molecular Weight | 1103.23 |