3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine

Modify Date: 2024-01-11 17:45:48

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine Structure
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine structure
 Common Name 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
CAS Number 81794-12-9 Molecular Weight 683.87
Density N/A Boiling Point N/A
Molecular Formula C37H45N5O6Si Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine


5’-O-(4,4’-Dimethoxytrityl)-3’-O-t-butyldimethylsilyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

 Names

Name Adenosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[(1,1-dimethylethyl)dimethylsilyl]
Synonym More Synonyms

  Biological Activity

Description 5’-O-(4,4’-Dimethoxytrityl)-3’-O-t-butyldimethylsilyl adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
Related Catalog
References

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.  

 Chemical & Physical Properties

Molecular Formula C37H45N5O6Si
Molecular Weight 683.87
Exact Mass 683.31400
PSA 136.00000
LogP 6.66430

 Synonyms

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine
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Chemsrc provides CAS#:81794-12-9 MSDS, density, melting point, boiling point, structure, etc. Its name is 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine>> amp version: 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-adenosine

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