2,4(1H,3H)-Pyrimidinedione, 3-(1,3-dihydro-3-oxo-1-isobenzofuranyl)-5- fluoro-

Modify Date: 2024-01-14 10:39:27

2,4(1H,3H)-Pyrimidinedione, 3-(1,3-dihydro-3-oxo-1-isobenzofuranyl)-5- fluoro- structure	Common Name	2,4(1H,3H)-Pyrimidinedione, 3-(1,3-dihydro-3-oxo-1-isobenzofuranyl)-5- fluoro-
	CAS Number	82023-29-8	Molecular Weight	262.19300
	Density	1.62g/cm3	Boiling Point	N/A
	Molecular Formula	C₁₂H₇FN₂O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Name	5-fluoro-3-(3-oxo-1H-2-benzofuran-1-yl)-1H-pyrimidine-2,4-dione
Synonym	More Synonyms

Density	1.62g/cm3
Molecular Formula	C₁₂H₇FN₂O₄
Molecular Weight	262.19300
Exact Mass	262.03900
PSA	81.42000
LogP	0.80530
Index of Refraction	1.664

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YR0430000

CHEMICAL NAME :: Uracil, 5-fluoro-3-phthalidyl-

CAS REGISTRY NUMBER :: 82023-29-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C12-H7-F-N2-O4

MOLECULAR WEIGHT :: 262.21

WISWESSER LINE NOTATION :: T56 BVO DHJ D- CT6MVNVJ EF

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - muscle weakness Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 25,1219,1982

3-(1,3-dihydro-...

CAS#:82033-51-0

~82%

2,4(1H,3H)-Pyri...

CAS#:82023-29-8

Literature: Kamata; Haga; Matsui; Nagata Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3160 - 3175

Fluorouracil

CAS#:51-21-8

3-BROMO PHTHALIDE

CAS#:6940-49-4

2,4(1H,3H)-Pyri...

CAS#:82023-29-8

Literature: Grelan Pharmaceutical Co., Ltd. Patent: US4528372 A1, 1985 ;

1,3-bis(1,3-dih...

CAS#:82104-77-6

~48%

2,4(1H,3H)-Pyri...

CAS#:82023-29-8

Literature: Kamata; Haga; Matsui; Nagata Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3160 - 3175

S-octyl 5-fluor...

CAS#:90162-91-7

~94%

2,4(1H,3H)-Pyri...

CAS#:82023-29-8

Literature: Ozaki, Shoichiro; Watanabe, Yutaka; Fujisawa, Hiroshi; Hoshiko, Tomonori Heterocycles, 1984 , vol. 22, # 3 p. 527 - 530

N/A

CAS#:104861-76-9

2,4(1H,3H)-Pyri...

CAS#:82023-29-8

Literature: Kamata; Haga; Matsui; Nagata Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3160 - 3175

3-BROMO PHTHALIDE

CAS#:6940-49-4

2,4(1H,3H)-Pyri...

CAS#:82023-29-8

Literature: Kametani, Tetsuji; Kigasawa, Kazuo; Hiiragi, Mineharu; Wakisaka, Kikuo; Nakazato, Kikuo; et al. Journal of Medicinal Chemistry, 1982 , vol. 25, # 10 p. 1219 - 1222

3-Pfu

N3-phthalidyl-5-fluorouracil

Uracil,5-fluoro-3-phthalidyl

5-Fluoro-3-phthalidyl-uracil

Dichloromethane
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sodium carbonate
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Silicon dioxide
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Triethanolamine
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Demeton
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2,4(1H,3H)-Pyrimidinedione, 3-(1,3-dihydro-3-oxo-1-isobenzofuranyl)-5- fluoro-

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Synonyms