FEN1-IN-5

Modify Date: 2024-01-13 18:28:26

Use of FEN1-IN-5

FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=12 nM), involving in DNA repair[1].

Name	FEN1-IN-5

Description	FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 (FEN1, IC50=12 nM), involving in DNA repair[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> FLAP
References	[1]. Wadhwa P, et al. QSAR and Docking Studies of N-hydroxy Urea Derivatives as Flap Endonuclease-1 Inhibitors. Curr Comput Aided Drug Des. 2015;11(4):346-52.

Molecular Formula	C₂₁H₁₇N₃O₄S
Molecular Weight	407.44
InChIKey	NZMGQXQQSAFNLL-UHFFFAOYSA-N
SMILES	CC(=O)Nc1cccc(-c2cccc(Cn3c(=O)n(O)c(=O)c4sccc43)c2)c1