Albutoin

Modify Date: 2024-01-04 12:52:54

Albutoin Structure
Albutoin structure
Common Name Albutoin
CAS Number 830-89-7 Molecular Weight 212.31200
Density 1.12g/cm3 Boiling Point 275.2ºC at 760 mmHg
Molecular Formula C10H16N2OS Melting Point N/A
MSDS N/A Flash Point 120.3ºC

 Use of Albutoin


Albutoin (BAX 422Z), an anticonvulsant agent, is a thiohydantoin derivative used for the research of grand mal epilepsies[1].

 Names

Name 5-(2-methylpropyl)-3-prop-2-enyl-2-sulfanylideneimidazolidin-4-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.12g/cm3
Boiling Point 275.2ºC at 760 mmHg
Molecular Formula C10H16N2OS
Molecular Weight 212.31200
Flash Point 120.3ºC
Exact Mass 212.09800
PSA 71.47000
LogP 1.08860
Index of Refraction 1.558

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
NJ0775300
CHEMICAL NAME :
4-Imidazolidinone, 5-(2-methylpropyl)-3-(2-propenyl)-2-thioxo-
CAS REGISTRY NUMBER :
830-89-7
BEILSTEIN REFERENCE NO. :
0163719
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C10-H16-N2-O-S
MOLECULAR WEIGHT :
212.34

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
785 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,107,1961
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
294 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,107,1961 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
500 mg/kg/10D-I
TOXIC EFFECTS :
Endocrine - evidence of thyroid hypofunction Endocrine - changes in thyroid weight Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,107,1961
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
10200 mg/kg/17D-I
TOXIC EFFECTS :
Behavioral - tolerance
REFERENCE :
TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 3,107,1961

 Safety Information

HS Code 2933990090

 Synthetic Route

~%

Albutoin Structure

Albutoin

CAS#:830-89-7

Literature: Oba et al. Nippon Shashin Gakkaishi, 1950 , vol. 13, p. 103,107 Chem.Abstr., 1952 , p. 3885

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-Allyl-5-isobutyl-2-thiohydantoin
BAX 422 Z
Euprax
3-allyl-5-isobutyl-2-thioxo-imidazolidin-4-one
ALBUTOIN
Coord