6-dimethylamino-2'-deoxyguanosine

Modify Date: 2024-01-03 10:54:22

6-dimethylamino-2'-deoxyguanosine Structure
6-dimethylamino-2'-deoxyguanosine structure
Common Name 6-dimethylamino-2'-deoxyguanosine
CAS Number 83061-20-5 Molecular Weight 294.31
Density 1.7±0.1 g/cm3 Boiling Point 665.6±65.0 °C at 760 mmHg
Molecular Formula C12H18N6O3 Melting Point N/A
MSDS N/A Flash Point 356.4±34.3 °C

 Use of 6-dimethylamino-2'-deoxyguanosine


2-Amino-2’-deoxy-N6,N6-dimethyl-2’-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-Amino-2'-deoxy-N,N-dimethyladenosine
Synonym More Synonyms

 6-dimethylamino-2'-deoxyguanosine Biological Activity

Description 2-Amino-2’-deoxy-N6,N6-dimethyl-2’-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 665.6±65.0 °C at 760 mmHg
Molecular Formula C12H18N6O3
Molecular Weight 294.31
Flash Point 356.4±34.3 °C
Exact Mass 294.144043
LogP -0.01
Vapour Pressure 0.0±2.1 mmHg at 25°C
Index of Refraction 1.776

 Synonyms

Adenosine, 2-amino-2'-deoxy-N,N-dimethyl-
2-Amino-2'-deoxy-N,N-dimethyladenosine
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