Mifamurtide
Mifamurtide structure
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Common Name | Mifamurtide | ||
|---|---|---|---|---|
| CAS Number | 83461-56-7 | Molecular Weight | 1237.499 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C59H109N6O19P | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of MifamurtideMifamurtide(CGP19835; MTP-PE) is a drug against osteosarcoma.Target: OthersMifamurtide is an immunomodulator with antitumor effects that appear to be mediated via activation of monocytes and macrophages. Mifamurtide is generally well tolerated; adverse events attributed to administration of the drug include chills, fever, headache, nausea, and myalgias. Based on the available data, mifamurtide can be considered for inclusion in treatment protocols for localized osteosarcoma [1]. Mifamurtide has orphan drug status for the treatment of osteosarcoma in the US and EU [2]. |
| Name | mifamurtide |
|---|---|
| Synonym | More Synonyms |
| Description | Mifamurtide(CGP19835; MTP-PE) is a drug against osteosarcoma.Target: OthersMifamurtide is an immunomodulator with antitumor effects that appear to be mediated via activation of monocytes and macrophages. Mifamurtide is generally well tolerated; adverse events attributed to administration of the drug include chills, fever, headache, nausea, and myalgias. Based on the available data, mifamurtide can be considered for inclusion in treatment protocols for localized osteosarcoma [1]. Mifamurtide has orphan drug status for the treatment of osteosarcoma in the US and EU [2]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C59H109N6O19P |
| Molecular Weight | 1237.499 |
| Exact Mass | 1236.748535 |
| PSA | 385.91000 |
| LogP | 10.98 |
| Index of Refraction | 1.530 |
| Storage condition | 2-8℃ |
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Muramyl tripeptide (mifamurtide) for the treatment of osteosarcoma.
Expert Rev. Anticancer Ther. 9(8) , 1035-49, (2009) Osteosarcoma is an ultraorphan disease. There are approximately 1000 new patients diagnosed with osteosarcoma each year in the USA and Europe. Current treatment for osteosarcoma utilizes multiagent ch... |
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Imunomodulative effect of liposomized muramyltripeptide phosphatidylethanolamine (L-MTP-PE) on mice with alveolar echinococcosis and treated with albendazole.
Parasitol. Res. 103(4) , 919-29, (2008) The effect of liposomized muramyltripeptide phosphatidylethanolamine (L-MTP-PE) administered separately or with anthelmintic albendazole (ABZ) on cellular immunity of mice with alveolar echinococcosis... |
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In vitro and in vivo enhancement of canine pulmonary alveolar macrophage cytotoxic activity against canine osteosarcoma cells.
Cancer Biother. Radiopharm. 14(2) , 121-8, (1999) The combination of chemotherapy with immunotherapy may offer an advantage over either therapy alone and provide a greater potential for total tumor eradication. Monocyte/macrophage-mediated tumor cell... |
| Mifamurtide |
| muramyl tripeptide phosphatidylethanolamine |
| (2R,5S,8R,13S,22R)-2-{[(3R,4R,5S,6R)-3-Acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-4-yl]oxy}-8-carbamoyl-19-hydroxy-5,13-dimethyl-19-oxido-3,6,11,14,25-pentaoxo-18,20,24-trioxa-4,7,12 ;,15-tetraaza-19λ-phosphatetracontan-22-yl hexadecanoate |
| N-Acetylmuramyl-alanyl-isoglutaminyl-alanyl-sn-glycero-3-phosphoethano lamine |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Mifamurtide
- Price: Click To Check
- Purity: 99.0%
- Delivery: 10 Day
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- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Mifamurtide
- Price: ￥6708.0/50g ￥1578.0/10g
- Purity: 98.0%
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- DC Chemicals Limited
- China
- Product Name: Mifamurtide
- Price: ￥Inquiry/100mg ￥Inquiry/250mg ￥Inquiry/1g
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- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: N-Acetylmuramyl-alanyl-isoglutaminyl-alanyl-sn-glycero-3-phosphoethano lamine
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
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- Contact: Ms Wang
- Email: enquiry@dycnchem.com
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: Mifamurtide
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Delivery: Inquiry
- Contact: Anson
- Email: info@tianfuchem.com
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