3-(1H-Benzimidazol-2-yl)-2(1H)-quinolinone

Modify Date: 2026-07-11 15:55:10

3-(1H-Benzimidazol-2-yl)-2(1H)-quinolinone Structure
3-(1H-Benzimidazol-2-yl)-2(1H)-quinolinone structure
Common Name 3-(1H-Benzimidazol-2-yl)-2(1H)-quinolinone
CAS Number 83520-73-4 Molecular Weight 261.27800
Density N/A Boiling Point N/A
Molecular Formula C16H11N3O Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 3-(1H-Benzimidazol-2-yl)-2(1H)-quinolinone
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C16H11N3O
Molecular Weight 261.27800
Exact Mass 261.09000
PSA 61.80000
LogP 3.48370

 Safety Information

HS Code 2933990090

 Synthetic Route

~80%

3-(1H-Benzimidazol-2-yl)-2(1H)-quinolinone Structure

3-(1H-Benzimida...

CAS#:83520-73-4

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Literature: Renhowe, Paul A.; Pecchi, Sabina; Shafer, Cynthia M.; Machajewski, Timothy D.; Jazan, Elisa M.; Taylor, Clarke; Antonios-McCrea, William; McBride, Christopher M.; Frazier, Kelly; Wiesmann, Marion; Lapointe, Gena R.; Feucht, Paul H.; Warne, Robert L.; Heise, Carla C.; Menezes, Daniel; Aardalen, Kimberly; Ye, Helen; He, Molly; Le, Vincent; Vora, Jayesh; Jansen, Johanna M.; Wernette-Hammond, Mary Ellen; Harris, Alex L. Journal of Medicinal Chemistry, 2009 , vol. 52, # 2 p. 278 - 292

~85%

3-(1H-Benzimidazol-2-yl)-2(1H)-quinolinone Structure

3-(1H-Benzimida...

CAS#:83520-73-4

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Literature: Abonia, Rodrigo; Castillo, Juan; Cuervo, Paola; Insuasty, Braulio; Quiroga, Jairo; Ortiz, Alejandro; Nogueras, Manuel; Cobo, Justo European Journal of Organic Chemistry, 2010 , # 2 p. 317 - 325

~29%

3-(1H-Benzimidazol-2-yl)-2(1H)-quinolinone Structure

3-(1H-Benzimida...

CAS#:83520-73-4

Learn More
Literature: Abonia, Rodrigo; Castillo, Juan; Cuervo, Paola; Insuasty, Braulio; Quiroga, Jairo; Ortiz, Alejandro; Nogueras, Manuel; Cobo, Justo European Journal of Organic Chemistry, 2010 , # 2 p. 317 - 325

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Bioassay

View more

Name: Upregulation of p53 protein expression in human HepG2 cells at 10 uM after 12 hrs by ...
Source: ChEMBL
Target: HepG2
External Id: CHEMBL4274189
Name: Cytotoxicity against human SKOV3 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: SK-OV-3
External Id: CHEMBL4274108
Name: Cytotoxicity against human HepG2 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: HepG2
External Id: CHEMBL4274107
Name: Inhibition of VEGF-mediated proliferation of HMVEC after 72 hrs
Source: ChEMBL
Target: NON-PROTEIN TARGET
External Id: CHEMBL1011002
Name: Inhibition of human recombinant FGFR1
Source: ChEMBL
Target: Fibroblast growth factor receptor 1
External Id: CHEMBL1010125
Name: Inhibition of VEGF receptor 2 mediated phosphorylation of poly-Glu/Tyr (4:1)
Source: ChEMBL
Target: Vascular endothelial growth factor receptor 2
External Id: CHEMBL820698
Name: Inhibition of human recombinant PDGFRbeta
Source: ChEMBL
Target: Platelet-derived growth factor receptor beta
External Id: CHEMBL1011001
Name: Cytotoxicity against human Bel7404 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: BEL-7404 tumor cell line
External Id: CHEMBL4274110
Name: Inhibition of human recombinant VEGFR2
Source: ChEMBL
Target: Vascular endothelial growth factor receptor 2
External Id: CHEMBL1010124
Name: Cytotoxicity against human NCI-H460 cells after 48 hrs by MTT assay
Source: ChEMBL
Target: NCI-H460
External Id: CHEMBL4274109
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 Synonyms

3-benzimidazol-2-ylhydroquinolin-2-one
3-Benzimidazol-1-yl-propylamin
3-benzimidazolylpropylamine
3-benzimidazol-1-yl-propylamine
benzimidazolylpropylamine
1H-benzimidazole-1-propanamine
3-Benzoimidazol-1-yl-propylamine
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