1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin- 2-one

Modify Date: 2024-01-03 13:53:47

1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin- 2-one Structure
1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin- 2-one structure
Common Name 1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin- 2-one
CAS Number 84044-26-8 Molecular Weight 342.78000
Density 1.32g/cm3 Boiling Point 628ºC at 760 mmHg
Molecular Formula C17H15ClN4O2 Melting Point N/A
MSDS N/A Flash Point 333.6ºC

 Names

Name 1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin- 2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.32g/cm3
Boiling Point 628ºC at 760 mmHg
Molecular Formula C17H15ClN4O2
Molecular Weight 342.78000
Flash Point 333.6ºC
Exact Mass 342.08800
PSA 73.80000
LogP 2.28000
Index of Refraction 1.665

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG5105000
CHEMICAL NAME :
Benzoic acid, 2-(7-chloro-1-methyl-2-oxo-5-phenyl-2,3-dihydro-1H-1, 4-benzodiazepin-3-yl) hydrazide
CAS REGISTRY NUMBER :
84044-26-8
LAST UPDATED :
199803
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C23-H19-Cl-N4-O2
MOLECULAR WEIGHT :
418.91

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
800 mg/kg
TOXIC EFFECTS :
Behavioral - anticonvulsant Behavioral - altered sleep time (including change in righting reflex) Behavioral - somnolence (general depressed activity)
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 16,617,1982

 Synthetic Route

~84%

1-Methyl-7-chloro-5-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin- 2-one Structure

1-Methyl-7-chlo...

CAS#:84044-26-8

Literature: Gorbunov, V. I.; Gorbunova, S. M.; Khlienko, Zh. N.; Kurilenko, V. M. Pharmaceutical Chemistry Journal, 1982 , vol. 16, # 8 p. 617 - 622 Khimiko-Farmatsevticheskii Zhurnal, 1982 , vol. 16, # 8 p. 951 - 956

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

1-Methyl-7-chloro-5-phenyl-3-benzoylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin-2-one
1-Methyl-7-chloro-5-phenyl-3-acetylhydrazino-2,3-dihydro-1H-1,4-benzodiazepin-2-one