4-Methylhistamine hydrochloride

Modify Date: 2024-01-29 17:48:04

4-Methylhistamine hydrochloride Structure
4-Methylhistamine hydrochloride structure
Common Name 4-Methylhistamine hydrochloride
CAS Number 84103-51-5 Molecular Weight 161.63
Density N/A Boiling Point N/A
Molecular Formula C6H12ClN3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 4-Methylhistamine hydrochloride


4-Methylhistamine (hydrochloride) is a potent, high affinity H4 receptor agonist Ki of 7 nM. 4-Methylhistamine (hydrochloride) displays more than 100-fold selectivity over other human histamine receptor subtypes[1].

 Names

Name 2-(5-methyl-1H-imidazol-4-yl)ethan-1-amine hydrochloride

 4-Methylhistamine hydrochloride Biological Activity

Description 4-Methylhistamine (hydrochloride) is a potent, high affinity H4 receptor agonist Ki of 7 nM. 4-Methylhistamine (hydrochloride) displays more than 100-fold selectivity over other human histamine receptor subtypes[1].
Related Catalog
References

[1]. Lim HD, et.al. Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist. J Pharmacol Exp Ther. 2005 Sep;314(3):1310-21.  

 Chemical & Physical Properties

Molecular Formula C6H12ClN3
Molecular Weight 161.63
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