Gefitinib N-oxide
Modify Date: 2024-02-13 18:29:00
Gefitinib N-oxide structure
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Common Name | Gefitinib N-oxide | ||
|---|---|---|---|---|
| CAS Number | 847949-51-3 | Molecular Weight | 462.90200 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H24ClFN4O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Gefitinib N-oxideGefitinib N-oxide is the N-oxide derivative of Gefitinib. Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells[1][2]. |
| Name | N-(3-chloro-4-fluorophenyl)-[7-methoxy-6-(3-(4-(1-oxymorpholinyl))propoxy)-4-quinazolin]amine |
|---|---|
| Synonym | More Synonyms |
| Description | Gefitinib N-oxide is the N-oxide derivative of Gefitinib. Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells[1][2]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 37 nM (Tyr1173 site, in NR6wtEGFR cells), 37 nM (Tyr992 site, in NR6wtEGFR cells)[1] |
| References |
| Molecular Formula | C22H24ClFN4O4 |
|---|---|
| Molecular Weight | 462.90200 |
| Exact Mass | 462.14700 |
| PSA | 94.93000 |
| LogP | 4.32000 |
| Gefitinib Morpholine N-oxide |
| Gefitinib N-Oxide |
| gefitinib N-oxide |
| Gefitinib Impurity 13 |