15-deoxy-Δ12,14-Prostaglandin D2 (15-deoxy-Δ12,14-PGD2)

Modify Date: 2024-09-08 21:06:05

15-deoxy-Δ12,14-Prostaglandin D2 (15-deoxy-Δ12,14-PGD2) Structure
15-deoxy-Δ12,14-Prostaglandin D2 (15-deoxy-Δ12,14-PGD2) structure
Common Name 15-deoxy-Δ12,14-Prostaglandin D2 (15-deoxy-Δ12,14-PGD2)
CAS Number 85235-11-6 Molecular Weight 334.450
Density 1.1±0.1 g/cm3 Boiling Point 535.0±50.0 °C at 760 mmHg
Molecular Formula C20H30O4 Melting Point N/A
MSDS N/A Flash Point 291.4±26.6 °C

 Use of 15-deoxy-Δ12,14-Prostaglandin D2 (15-deoxy-Δ12,14-PGD2)


15-deoxy-Δ12,14-PGD2 is a metabolite of PGD2 .1 It is an agonist of PGD2 receptor 2 (DP2) that binds DP2 (Ki = 50 nM for the mouse receptor expressed in HEK293 cell membranes) and induces activation of eosinophils

 Names

Name 7-[(1R,5S)-5-hydroxy-2-oct-2-enylidene-3-oxocyclopentyl]hept-5-enoic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 535.0±50.0 °C at 760 mmHg
Molecular Formula C20H30O4
Molecular Weight 334.450
Flash Point 291.4±26.6 °C
Exact Mass 334.214417
PSA 74.60000
LogP 3.37
Vapour Pressure 0.0±3.2 mmHg at 25°C
Index of Refraction 1.563

 Synonyms

(5Z,9α,12E,14E)-9-Hydroxy-11-oxoprosta-5,12,14-trien-1-oic acid
Prosta-5,12,14-trien-1-oic acid, 9-hydroxy-11-oxo-, (5Z,9α,12E,14E)-