CHEMICAL IDENTIFICATION
-
RTECS NUMBER :
-
BV8071500
-
CHEMICAL NAME :
-
5-alpha-Androstan-3-one, 17-beta-hydroxy-, propionate
-
CAS REGISTRY NUMBER :
-
855-22-1
-
BEILSTEIN REFERENCE NO. :
-
2628403
-
LAST UPDATED :
-
199612
-
DATA ITEMS CITED :
-
5
-
MOLECULAR FORMULA :
-
C22-H34-O3
-
MOLECULAR WEIGHT :
-
346.56
-
WISWESSER LINE NOTATION :
-
L E5 B666 OVTJ A1 E1 FOV2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
DOSE :
-
50 ug/kg
-
SEX/DURATION :
-
female 1 day(s) pre-mating
-
TOXIC EFFECTS :
-
Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Maternal Effects - uterus, cervix, vagina
-
REFERENCE :
-
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 30,55,1972
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
DOSE :
-
20 mg/kg
-
SEX/DURATION :
-
female 4 day(s) pre-mating
-
TOXIC EFFECTS :
-
Reproductive - Fertility - other measures of fertility
-
REFERENCE :
-
BIREBV Biology of Reproduction. (Soc. for the Study of Reproduction, 309 W. Clark St., Champaign, IL 61820) V.1- 1969- Volume(issue)/page/year: 20,384,1979
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
DOSE :
-
3 gm/kg
-
SEX/DURATION :
-
male 6 day(s) pre-mating
-
TOXIC EFFECTS :
-
Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands
-
REFERENCE :
-
JOENAK Journal of Endocrinology. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1939- Volume(issue)/page/year: 51,241,1971
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Subcutaneous
-
DOSE :
-
150 mg/kg
-
SEX/DURATION :
-
female 28-58 day(s) after conception
-
TOXIC EFFECTS :
-
Reproductive - Effects on Newborn - delayed effects
-
REFERENCE :
-
HOBEAO Hormones and Behavior. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1969- Volume(issue)/page/year: 6,139,1975
-
TYPE OF TEST :
-
TDLo - Lowest published toxic dose
-
ROUTE OF EXPOSURE :
-
Implant
-
DOSE :
-
208 mg/kg
-
SEX/DURATION :
-
male 82 day(s) pre-mating
-
TOXIC EFFECTS :
-
Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male
-
REFERENCE :
-
JRPFA4 Journal of Reproduction and Fertility. (Biochemical Soc. Book Depot, POB 32, Commerce Way, Colchester, Essex CO2 8HP, UK) V.1- 1960- Volume(issue)/page/year: 94,57,1992
|
