Tos-PEG3-O-C1-CH3COO

Modify Date: 2024-01-10 15:56:27

Tos-PEG3-O-C1-CH3COO Structure
Tos-PEG3-O-C1-CH3COO structure
Common Name Tos-PEG3-O-C1-CH3COO
CAS Number 855120-17-1 Molecular Weight 376.42
Density N/A Boiling Point N/A
Molecular Formula C16H24O8S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Tos-PEG3-O-C1-CH3COO


PROTAC Linker 6 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 6 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

 Names

Name PROTAC Linker 6

 Tos-PEG3-O-C1-CH3COO Biological Activity

Description PROTAC Linker 6 is a PROTAC linker, which refers to the alkyl/ether composition. PROTAC Linker 6 can be used in the synthesis of a series of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Related Catalog
Target

Alkyl/ether

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

 Chemical & Physical Properties

Molecular Formula C16H24O8S
Molecular Weight 376.42
Storage condition 2-8°C