Tedizolid Phosphate
Modify Date: 2024-01-02 17:56:16
Tedizolid Phosphate structure
|
Common Name | Tedizolid Phosphate | ||
|---|---|---|---|---|
| CAS Number | 856867-55-5 | Molecular Weight | 450.318 | |
| Density | 1.8±0.1 g/cm3 | Boiling Point | 725.6±70.0 °C at 760 mmHg | |
| Molecular Formula | C17H16FN6O6P | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 392.6±35.7 °C | |
Use of Tedizolid PhosphateTedizolid phosphate is a novel oxazolidinone with activity against Gram-positive pathogens. |
| Name | tedizolid phosphate |
|---|---|
| Synonym | More Synonyms |
| Description | Tedizolid phosphate is a novel oxazolidinone with activity against Gram-positive pathogens. |
|---|---|
| Related Catalog | |
| In Vitro | Tedizolid (0.25 μg/mL) inhibits all 28 clinical isolates of PRSP, and is 4-fold more potent than linezolid against PRSP[1]. |
| In Vivo | For mice infected with PSSP type III, the 100% survival rate is achieved with tedizolid phosphate at a minimum total daily dose of 10 mg/kg. Lungs of infected mice treated with tedizolid phosphate show less severe inflammation and edema, as indicated by the mean scores for inflammation and edema[1]. |
| Animal Admin | To induce a systemic S. pneumoniae infection, male ICR mice (weight, 18 to 20 g) are inoculated intraperitoneally with 1 of 4 PRSP isolates (DR9, DR10, DR11, or DR14) suspended in 10% mucin. The suspension contained sufficient bacteria to kill 100% of untreated control mice. At 1 h postinfection, mice receives a single dose of either tedizolid phosphate or linezolid, and survival is assessed daily for 7 days postinfection. Treatments are delivered both orally and intravenously at each of four doses (40 mg/kg of body weight, 13.33 mg/kg, 4.44 mg/kg, and 1.48 mg/kg), with 8 mice per group defined by dose, delivery method, and infecting strain. The 50% effective dose (ED50), i.e., the dose allowing survival of 50% of the infected mice, is calculated for each delivery route using probit analysis. |
| References |
| Density | 1.8±0.1 g/cm3 |
|---|---|
| Boiling Point | 725.6±70.0 °C at 760 mmHg |
| Molecular Formula | C17H16FN6O6P |
| Molecular Weight | 450.318 |
| Flash Point | 392.6±35.7 °C |
| Exact Mass | 450.085297 |
| PSA | 162.60000 |
| LogP | 0.69 |
| Vapour Pressure | 0.0±2.5 mmHg at 25°C |
| Index of Refraction | 1.739 |
| Storage condition | 2-8°C |
| 2-Oxazolidinone, 3-[3-fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl]-5-[(phosphonooxy)methyl]- |
| TR-701 FA |
| Torezolid phosphate |
| UNII-O7DRJ6R4DW |
| Tedizolid phosphate |
| [(5R)-3-[3-fluoro-4-[6-(2-methyltetrazol-5-yl)pyridin-3-yl]phenyl]-2-oxo-1,3-oxazolidin-5-yl]methyl dihydrogen phosphate |
| (3-{3-Fluoro-4-[6-(2-methyl-2H-tetrazol-5-yl)-3-pyridinyl]phenyl}-2-oxo-1,3-oxazolidin-5-yl)methyl dihydrogen phosphate |
| Tedizolid (phosphate) |
- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Tedizolid Phosphate
- Price: Click To Check
- Purity: 98.0%
- Delivery: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Tedizolid Phosphate
- Price: ￥606.0/50mg ￥2026.0/250mg ￥1016.0/100mg ￥406.0/25mg
- Purity: 98.0%
- Delivery: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Torezolid phosphate
- Price: $400.0/100mg $800.0/250mg $1600.0/1g
- Purity: 98.0%
- Delivery: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- ShangHai DC Chemicals Co.,Ltd
- China
- Product Name: Torezolid phosphate
- Price: ￥Inquiry/1g
- Purity: 98.9%
- Delivery: 1 Day
- Contact: Tony Lai
- Email: order@dcchemicals.com
- Henan Tianfu Chemical Co., Ltd.
- China
- Product Name: tedizolid phosphate
- Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
- Purity: 99.0%
- Delivery: Inquiry
- Contact: Anson
- Email: info@tianfuchem.com
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Price: $92/10mM*1mLinDMSO
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