Latanoprostene bunod

Modify Date: 2024-01-03 13:15:32

Latanoprostene bunod Structure
Latanoprostene bunod structure
Common Name Latanoprostene bunod
CAS Number 860005-21-6 Molecular Weight 507.62
Density N/A Boiling Point N/A
Molecular Formula C27H41NO8 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Latanoprostene bunod


Latanoprostene bunod (LBN), a nitric oxide (NO)-donating prostaglandin F2a analog, is a topical ophthalmic therapeutic for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT) [1].

 Names

Name 4-nitrooxybutyl (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
Synonym More Synonyms

 Latanoprostene bunod Biological Activity

Description Latanoprostene bunod (LBN), a nitric oxide (NO)-donating prostaglandin F2a analog, is a topical ophthalmic therapeutic for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension (OHT) [1].
Related Catalog
References

[1]. Cavet ME, et al. The Role of Nitric Oxide in the Intraocular Pressure Lowering Efficacy of Latanoprostene Bunod: Review of Nonclinical Studies. J Ocul Pharmacol Ther. 2018 Jan/Feb;34(1-2):52-60.

 Chemical & Physical Properties

Molecular Formula C27H41NO8
Molecular Weight 507.62
Exact Mass 507.28300
PSA 142.04000
LogP 4.28970

 Synonyms

NCX-116
UNII-I6393O0922
Latanoprostene BUNOD