MK-8591
Modify Date: 2024-01-10 13:02:56
MK-8591 structure
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Common Name | MK-8591 | ||
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| CAS Number | 865363-93-5 | Molecular Weight | 293.2537832 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C12H12FN5O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of MK-8591MK-8591 is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. |
| Name | 4'-ethynyl-2-fluoro-2'-deoxyadenosine |
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| Synonym | More Synonyms |
| Description | MK-8591 is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively. |
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| Related Catalog | |
| Target |
HIV-1 (WT):0.068 nM (EC50) HIV-1 (MDR):0.15 nM (EC50) HIV-1 (M184V):3.1 nM (EC50) |
| In Vitro | MK-8591 (4'Ed2FA) is a potent anti-HIV-1 agent, acting as a nucleoside reverse transcriptase inhibitor, with EC50s of 0.068 nM, 3.1 nM and 0.15 nM for HIV-1 (WT), HIV-1 (M184V), HIV-1 (MDR), respectively[1]. |
| References |
| Molecular Formula | C12H12FN5O3 |
|---|---|
| Molecular Weight | 293.2537832 |
| MK-8591 |