ARL 17477 dihydrochloride

Modify Date: 2025-09-20 13:43:41

ARL 17477 dihydrochloride Structure
ARL 17477 dihydrochloride structure
 Common Name ARL 17477 dihydrochloride
CAS Number 866914-87-6 Molecular Weight 442.83
Density N/A Boiling Point N/A
Molecular Formula C20H22Cl3N3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ARL 17477 dihydrochloride


ARL-17477 is a dual inhibitor of NOS1and the autophagy-lysosomal system with anticancer activity and can inhibit tumor growth in KRAS-mutated cancers[1].

 Names

Name N-(4-{2-[(3-Chlorobenzyl)amino]ethyl}phenyl)-2-thiophenecarboximi damide dihydrochloride

 ARL 17477 dihydrochloride Biological Activity

Description ARL-17477 is a dual inhibitor of NOS1and the autophagy-lysosomal system with anticancer activity and can inhibit tumor growth in KRAS-mutated cancers[1].
Related Catalog
References

[1]. Teiko Komori Nomura, et al. ARL-17477 is a dual inhibitor of NOS1 and the autophagic-lysosomal system that prevents tumor growth in vitro and in vivo. Sci Rep. 2023 Jul 4;13(1):10757.  

 Chemical & Physical Properties

Molecular Formula C20H22Cl3N3S
Molecular Weight 442.83
Exact Mass 441.06000
PSA 78.65000
LogP 7.46600
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Chemsrc provides ARL 17477 dihydrochloride(CAS#:866914-87-6) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of ARL 17477 dihydrochloride are included as well.>> amp version: ARL 17477 dihydrochloride

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