NIAD-4
Modify Date: 2024-01-10 19:03:20
NIAD-4 structure
|
Common Name | NIAD-4 | ||
|---|---|---|---|---|
| CAS Number | 868592-56-7 | Molecular Weight | 334.41500 | |
| Density | 1.385±0.06 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C18H10N2OS2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of NIAD-4NIAD-4 is a fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM[1]. |
| Name | 2-[[5-[5-(4-hydroxyphenyl)thiophen-2-yl]thiophen-2-yl]methylidene]propanedinitrile |
|---|---|
| Synonym | More Synonyms |
| Description | NIAD-4 is a fluorophore for optical imaging of amyloid-β (Aβ) in the central nervous system (CNS) for Alzheimer’s disease (AD). NIAD-4 binds to the same Aβ site with the binding affinity (Ki) of 10 nM[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.385±0.06 g/cm3 |
|---|---|
| Molecular Formula | C18H10N2OS2 |
| Molecular Weight | 334.41500 |
| Exact Mass | 334.02300 |
| PSA | 124.29000 |
| LogP | 5.27976 |
| Water Solubility | Insuluble (1.6E-3 g/L) (25 ºC) |
| Propanedinitrile,[[5'-(4-hydroxyphenyl)[2,2'-bithiophen]-5-yl]methylene] |
| [[5-(4-Hydroxyphenyl)[2,2-bithiophen]-5-yl]methylene]-propanedinitrile |
| NIAD-4 |
| 2-[[5'-(4-Hydroxyphenyl)[2,2'-bithiophen]-5-yl]methylene]propanedinitrile |