(D-Pro4,D-Trp7·9·10)-Substance P (4-11)

Modify Date: 2024-01-31 22:20:58

(D-Pro4,D-Trp7·9·10)-Substance P (4-11) Structure
(D-Pro4,D-Trp7·9·10)-Substance P (4-11) structure
Common Name (D-Pro4,D-Trp7·9·10)-Substance P (4-11)
CAS Number 86917-57-9 Molecular Weight 1207.40000
Density N/A Boiling Point N/A
Molecular Formula C62H74N14O10S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (D-Pro4,D-Trp7·9·10)-Substance P (4-11)


[D-Pro4,D-Trp7,9,10] Substance P (4-11) is a potent tachykinin antagonist[1].

 Names

Name [D-Pro4,D-Trp7,9,10]-Substance P (4-11)
Synonym More Synonyms

 (D-Pro4,D-Trp7·9·10)-Substance P (4-11) Biological Activity

Description [D-Pro4,D-Trp7,9,10] Substance P (4-11) is a potent tachykinin antagonist[1].
Related Catalog
References

[1]. Bailey SJ, et al. Effect of the tachykinin antagonist, [D-Pro4, D-Trp7,9,10] substance P-(4-11), on tachykinin- and histamine-induced inositol phosphate generation in intestinal smooth muscle. Naunyn Schmiedebergs Arch Pharmacol. 1987 Mar;335(3):296-300.  

 Chemical & Physical Properties

Molecular Formula C62H74N14O10S
Molecular Weight 1207.40000
Exact Mass 1206.54000
PSA 417.67000
LogP 6.48210

 Safety Information

WGK Germany 3

 Synonyms

(D-pro4,D-trp7,9,10)-substance P*fragment 4-11
Gpant-1,Ptt-SP (4-11)
Substance P,fragment 4-11,[D-Pro4,D-Trp7,9,10]
DPRO-GLN-GLN-DTRP-PHE-DTRP-DTRP-MET-NH2
(D-PRO4,D-TRP7,9,10)-SUBSTANCE P (4-11)
D-Pro-L-Glu(NH2)-L-Glu(NH2)-D-Trp-L-Phe-D-Trp-D-Trp-L-Met-NH2
D-Pro-L-Gln-L-Gln-D-Trp-L-Phe-D-Trp-D-Trp-L-Met-NH2
D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-MET-NH2
H-D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2