Monomethyl auristatin E intermediate-11

Modify Date: 2024-01-17 01:53:10

Monomethyl auristatin E intermediate-11 structure	Common Name	Monomethyl auristatin E intermediate-11
	CAS Number	870640-62-3	Molecular Weight	221.33852
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₄H₂₃NO	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Monomethyl auristatin E intermediate-11

Monomethyl auristatin E intermediate-11 is an intermediate reactant in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

Name	(2S,3S)-2-(benzyl(methyl)amino)-3-methylpentan-1-ol

Description	Monomethyl auristatin E intermediate-11 is an intermediate reactant in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87.

Molecular Formula	C₁₄H₂₃NO
Molecular Weight	221.33852

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: (2S,3S)-2-(benzyl(methyl)amino)-3-methylpentan-1-ol
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Monomethyl auristatin E intermediate-11

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