AX 048
Modify Date: 2025-08-26 21:33:00
AX 048 structure
|
Common Name | AX 048 | ||
|---|---|---|---|---|
| CAS Number | 873079-69-7 | Molecular Weight | 383.565 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C22H41NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of AX 048AX-048is a potent group IVA cPLA2 inhibitor. The group IVA phospholipase A2 (PLA2), known as calcium-dependent cytosolic PLA2 (cPLA2), selectively releases arachidonic acid from membrane phospholipids, playing a central role in initiating the synthesis of prostaglandins and leukotrienes. |
| Name | ethyl 4-(2-oxohexadecanoylamino)butanoate |
|---|---|
| Synonym | More Synonyms |
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Molecular Formula | C22H41NO4 |
| Molecular Weight | 383.565 |
| Exact Mass | 383.303558 |
| PSA | 72.47000 |
| LogP | 6.81 |
| Index of Refraction | 1.462 |
| InChIKey | FMFKQXKYWWJNJS-UHFFFAOYSA-N |
| SMILES | CCCCCCCCCCCCCCC(=O)C(=O)NCCCC(=O)OCC |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
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Name: Inhibition of secretory phospholipase A2 in rat renal mesangial cells assessed as sup...
Source: ChEMBL
Target: N/A
External Id: CHEMBL3807448
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Name: Inhibition of human group 4A cPLA2 using PAPC as substrate preincubated for 5 mins wi...
Source: ChEMBL
Target: Cytosolic phospholipase A2
External Id: CHEMBL4432422
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|
Name: Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of Kdo2 lipi...
Source: ChEMBL
Target: RAW264.7
External Id: CHEMBL1042149
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Name: Inhibition of human group 6A iPLA2 using PAPC as substrate preincubated for 5 mins wi...
Source: ChEMBL
Target: 85/88 kDa calcium-independent phospholipase A2
External Id: CHEMBL4432423
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| Butanoic acid, 4-[(1,2-dioxohexadecyl)amino]-, ethyl ester |
| unii-8782z45dlv |
| ax 048 |
| Ethyl 4-[(2-oxohexadecanoyl)amino]butanoate |