PPY A
Modify Date: 2024-01-10 19:31:55
PPY A structure
|
Common Name | PPY A | ||
|---|---|---|---|---|
| CAS Number | 875634-01-8 | Molecular Weight | 372.42000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C22H20N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PPY APPY-A is a potent T315I mutant and wild-type Abl kinases inhibitor with IC50s of 9 and 20 nM, respectively. PPY-A inhibits Ba⁄F3 cells transformed with wild-type Abl and Abl T315I mutantl with IC50s of 390 and 180 nM, respectively. PPY-A can be used for the research of chronic myeloid leukemia (CML)[1]. |
| Name | 5-[3-(2-Methoxyphenyl)-1H-pyrrolo[2,3-b]pyridin-5-yl]-N,N-dimethy lnicotinamide |
|---|
| Description | PPY-A is a potent T315I mutant and wild-type Abl kinases inhibitor with IC50s of 9 and 20 nM, respectively. PPY-A inhibits Ba⁄F3 cells transformed with wild-type Abl and Abl T315I mutantl with IC50s of 390 and 180 nM, respectively. PPY-A can be used for the research of chronic myeloid leukemia (CML)[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C22H20N4O2 |
|---|---|
| Molecular Weight | 372.42000 |
| Exact Mass | 372.15900 |
| PSA | 71.11000 |
| LogP | 4.00230 |