4-ethyl-3-(4-imidazol-1-ylphenyl)-4,5-dihydro-1H-pyridazin-6-one
Modify Date: 2024-01-10 19:10:07
4-ethyl-3-(4-imidazol-1-ylphenyl)-4,5-dihydro-1H-pyridazin-6-one structure
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Common Name | 4-ethyl-3-(4-imidazol-1-ylphenyl)-4,5-dihydro-1H-pyridazin-6-one | ||
|---|---|---|---|---|
| CAS Number | 88427-75-2 | Molecular Weight | 268.31400 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H16N4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
| Name | 4-ethyl-3-(4-imidazol-1-ylphenyl)-4,5-dihydro-1H-pyridazin-6-one |
|---|
| Molecular Formula | C15H16N4O |
|---|---|
| Molecular Weight | 268.31400 |
| Exact Mass | 268.13200 |
| PSA | 62.77000 |
| LogP | 1.83400 |
| InChIKey | IFMSLEJMFHOWPL-UHFFFAOYSA-N |
| SMILES | CCC1CC(=O)NN=C1c1ccc(-n2ccnc2)cc1 |
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~44%
4-ethyl-3-(4-im... CAS#:88427-75-2 |
| Literature: Sircar, Ila; Duell, Bradley L.; Bobowski, George; Bristol, James A.; Evans, Dale B. Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1405 - 1413 |
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~%
4-ethyl-3-(4-im... CAS#:88427-75-2 |
| Literature: Sircar, Ila; Duell, Bradley L.; Bobowski, George; Bristol, James A.; Evans, Dale B. Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1405 - 1413 |
|
~%
4-ethyl-3-(4-im... CAS#:88427-75-2 |
| Literature: Sircar, Ila; Duell, Bradley L.; Bobowski, George; Bristol, James A.; Evans, Dale B. Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1405 - 1413 |
|
~%
4-ethyl-3-(4-im... CAS#:88427-75-2 |
| Literature: Sircar, Ila; Duell, Bradley L.; Bobowski, George; Bristol, James A.; Evans, Dale B. Journal of Medicinal Chemistry, 1985 , vol. 28, # 10 p. 1405 - 1413 |
| Precursor 2 | |
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| DownStream 0 | |
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Name: Ratio of IC50 values for PDE III and PDE I.
Source: ChEMBL
Target: N/A
External Id: CHEMBL844591
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Name: Ratio of IC50 values for PDE III and PDE II.
Source: ChEMBL
Target: N/A
External Id: CHEMBL844592
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|
Name: Inhibitory concentration against cGMP PDE I enzyme in guinea pig
Source: ChEMBL
Target: Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
External Id: CHEMBL765554
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Name: Inhibition of cGMP PDE II enzyme in guinea pig at 1E-5M concentration
Source: ChEMBL
Target: cGMP-dependent 3',5'-cyclic phosphodiesterase
External Id: CHEMBL759146
|
|
Name: Inhibitory concentration against cAMP PDE I enzyme in guinea pig
Source: ChEMBL
Target: Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
External Id: CHEMBL765553
|
|
Name: Inhibition of cGMP PDE II enzyme in guinea pig at 1E-4M concentration
Source: ChEMBL
Target: cGMP-dependent 3',5'-cyclic phosphodiesterase
External Id: CHEMBL759145
|
|
Name: Inhibitory concentration against cAMP PDE II enzyme in guinea pig
Source: ChEMBL
Target: cGMP-dependent 3',5'-cyclic phosphodiesterase
External Id: CHEMBL759151
|
|
Name: Evaluated for 50% increase of myocardial contractility in anesthetized dog, administe...
Source: ChEMBL
Target: Canis lupus familiaris
External Id: CHEMBL668573
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|
Name: Inhibition of cAMP PDE II enzyme in guinea pig at 1E-4M concentration.
Source: ChEMBL
Target: cGMP-dependent 3',5'-cyclic phosphodiesterase
External Id: CHEMBL765563
|
|
Name: Inhibitory concentration against cGMP PDE II enzyme in guinea pig
Source: ChEMBL
Target: cGMP-dependent 3',5'-cyclic phosphodiesterase
External Id: CHEMBL759152
|
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