(E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine

Modify Date: 2024-01-03 16:16:47

(E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine Structure
(E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine structure
Common Name (E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine
CAS Number 886230-76-8 Molecular Weight 320.388
Density 1.3±0.1 g/cm3 Boiling Point 562.8±50.0 °C at 760 mmHg
Molecular Formula C19H20N4O Melting Point N/A
MSDS N/A Flash Point 294.2±30.1 °C

 Names

Name 1-(oxan-2-yl)-3-(2-pyridin-2-ylethenyl)indazol-6-amine
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 562.8±50.0 °C at 760 mmHg
Molecular Formula C19H20N4O
Molecular Weight 320.388
Flash Point 294.2±30.1 °C
Exact Mass 320.163696
PSA 65.96000
LogP 2.02
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.676

 Synthetic Route

~95%

(E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine Structure

(E)-3-[2-(Pyrid...

CAS#:886230-76-8

Literature: PFIZER INC. Patent: WO2006/48761 A2, 2006 ; Location in patent: Page/Page column 31-32 ; WO 2006/048761 A2

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(E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine Structure

(E)-3-[2-(Pyrid...

CAS#:886230-76-8

Literature: CURIS, INC. Patent: WO2009/36066 A1, 2009 ; WO 2009/036066 A1

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(E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine Structure

(E)-3-[2-(Pyrid...

CAS#:886230-76-8

Literature: CURIS, INC. Patent: WO2009/36066 A1, 2009 ; WO 2009/036066 A1

~%

(E)-3-[2-(Pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine Structure

(E)-3-[2-(Pyrid...

CAS#:886230-76-8

Literature: CURIS, INC. Patent: WO2009/36066 A1, 2009 ; WO 2009/036066 A1

 Synonyms

1H-Indazol-6-amine, 3-[(E)-2-(2-pyridinyl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-
3-[(E)-2-(2-Pyridinyl)vinyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine
(E)-3-[2-(PYRIDIN-2-YL)ETHENYL]-1-(TETRAHYDRO-2H-PYRAN-2-YL)-1H-INDAZOL-6-AMINE
(E)-3-(2-(pyridin-2-yl)vinyl)-1-(tetrahydro-2H-pyran-2-yl)-1H-indazol-6-amine
6-amino-3-((E)-2-pyridin-2-yl-vinyl)-1-(tetrahydropyran-2-yl)-1H-indazole