SLc-nhs-(+)-biotin

Modify Date: 2024-01-07 10:45:35

SLc-nhs-(+)-biotin Structure
SLc-nhs-(+)-biotin structure
Common Name SLc-nhs-(+)-biotin
CAS Number 887628-40-2 Molecular Weight 524.67
Density N/A Boiling Point N/A
Molecular Formula C25H40N4O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of SLc-nhs-(+)-biotin


Biotin-C10-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Biotin-C10-NHS Ester
Synonym More Synonyms

 SLc-nhs-(+)-biotin Biological Activity

Description Biotin-C10-NHS Ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C25H40N4O6S
Molecular Weight 524.67

 Synonyms

MFCD05865045