WQ3810

Modify Date: 2024-09-14 21:09:11

WQ3810 Structure
WQ3810 structure
Common Name WQ3810
CAS Number 888032-58-4 Molecular Weight 461.43700
Density N/A Boiling Point N/A
Molecular Formula C22H22F3N5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of WQ3810


WQ3810 is an orally active fluoroquinolone, with potent antibacterial activities.

 Names

Name 1-(6-amino-3,5-difluoropyridin-2-yl)-6-fluoro-8-methyl-4-oxo-7-[3-(propan-2-ylamino)azetidin-1-yl]quinoline-3-carboxylic acid
Synonym More Synonyms

 WQ3810 Biological Activity

Description WQ3810 is an orally active fluoroquinolone, with potent antibacterial activities.
Related Catalog
In Vitro WQ-3810 shows potent activity against A. baumannii, including MDR isolates, with MIC90 of 1 mg/L, more than eight-fold higher than that of ciprofloxacin (64 mg/L) and levofloxacin (8 mg/L). WQ-3810 also exhibits inhibitory effects on E. coli and S. pneumoniae, including FQR isolates, with MIC90 of 4 mg/L and 0.06 mg/L, respectively. WQ-3810 is the most potent among the fluoroquinolones tested against meticillin-resistant Staphylococcus aureus (MRSA) and Neisseria gonorrhoeae, including FQR isolates[1].
References

[1]. Kazamori D, et al. In vitro activity of WQ-3810, a novel fluoroquinolone, against multidrug-resistant and fluoroquinolone-resistant pathogens. Int J Antimicrob Agents. 2014 Nov;44(5):443-9.

 Chemical & Physical Properties

Molecular Formula C22H22F3N5O3
Molecular Weight 461.43700
Exact Mass 461.16700
PSA 114.21000
LogP 2.96440

 Synonyms

KPI-10 free base
WQ-3810
UNII-RTQ8P0159M
WQ3810
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