3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine

Modify Date: 2025-08-20 16:42:38

3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine Structure
3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine structure
Common Name 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine
CAS Number 89947-86-4 Molecular Weight 667.87
Density N/A Boiling Point N/A
Molecular Formula C37H45N5O5Si Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine


3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 3'-O-(t-Butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine

  Biological Activity

Description 3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C37H45N5O5Si
Molecular Weight 667.87
InChIKey BLILIIKIHHYPLG-DCMFLLSESA-N
SMILES COc1ccc(C(OCC2OC(n3cnc4c(N)ncnc43)CC2O[Si](C)(C)C(C)(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1
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