2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine

Modify Date: 2024-01-11 14:16:30

2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine Structure
2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine structure
Common Name 2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine
CAS Number 899827-82-8 Molecular Weight 285.23
Density 2.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C10H12FN5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine


2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 6-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-3,9-dihydro-2H-purin-2-one
Synonym More Synonyms

  Biological Activity

Description 2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 2.2±0.1 g/cm3
Molecular Formula C10H12FN5O4
Molecular Weight 285.23
Exact Mass 285.087341
LogP -2.23
Index of Refraction 1.876

 Synonyms

6-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-3,9-dihydro-2H-purin-2-one
MFCD25542486
2H-Purin-2-one, 6-amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-3,9-dihydro-