Bis[hydroxy(phenyl)methyl]phosphinic acid

Modify Date: 2025-09-21 10:11:41

Bis[hydroxy(phenyl)methyl]phosphinic acid Structure
Bis[hydroxy(phenyl)methyl]phosphinic acid structure
Common Name Bis[hydroxy(phenyl)methyl]phosphinic acid
CAS Number 90-09-5 Molecular Weight 278.24000
Density 1.383g/cm3 Boiling Point 592.9ºC at 760 mmHg
Molecular Formula C14H15O4P Melting Point N/A
MSDS N/A Flash Point 312.4ºC

 Names

Name Bis[hydroxy(phenyl)methyl]phosphinic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.383g/cm3
Boiling Point 592.9ºC at 760 mmHg
Molecular Formula C14H15O4P
Molecular Weight 278.24000
Flash Point 312.4ºC
Exact Mass 278.07100
PSA 87.57000
LogP 2.63900
Index of Refraction 1.632
InChIKey YMIKTLVFXBBWKP-UHFFFAOYSA-N
SMILES O=P(O)(C(O)c1ccccc1)C(O)c1ccccc1

 Synthetic Route

~24%

Bis[hydroxy(phenyl)methyl]phosphinic acid Structure

Bis[hydroxy(phe...

CAS#:90-09-5

Literature: Albouy, Dominique; Etemad-Moghadam, Guita; Koenig, Max European Journal of Organic Chemistry, 1999 , # 4 p. 861 - 868

~83%

Bis[hydroxy(phenyl)methyl]phosphinic acid Structure

Bis[hydroxy(phe...

CAS#:90-09-5

Literature: Kaboudin, Babak; Haghighat, Hamideh Tetrahedron Letters, 2005 , vol. 46, # 46 p. 7955 - 7957

~96%

Bis[hydroxy(phenyl)methyl]phosphinic acid Structure

Bis[hydroxy(phe...

CAS#:90-09-5

Literature: Majewski, Piotr Synthesis, 1987 , # 6 p. 555 - 557

~40%

Bis[hydroxy(phenyl)methyl]phosphinic acid Structure

Bis[hydroxy(phe...

CAS#:90-09-5

Literature: Arbuzov, B. A.; Erastov, O. A.; Romanova, I. P.; Zyablikova, T. A. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1981 , vol. 30, # 12 p. 2336 - 2338 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1981 , # 12 p. 2803 - 2806

 Bioassay

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Name: Primary cell-based high-throughput screening assay for identification of compounds th...
Source: Johns Hopkins Ion Channel Center
Target: regulator of G-protein signaling 4 isoform 2 [Homo sapiens]
External Id: JHICC_RGS_Act_HTS
Name: Luminescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: mu-type opioid receptor isoform MOR-1 [Homo sapiens]
External Id: OPRM1-OPRD1_AG_LUMI_1536_1X%ACT PRUN
Name: QFRET-based biochemical primary high throughput screening assay to identify exosite i...
Source: The Scripps Research Institute Molecular Screening Center
Target: disintegrin and metalloproteinase domain-containing protein 17 preproprotein [Homo sapiens]
External Id: ADAM17_INH_QFRET_1536_1X%INH PRUN
Name: Fluorescence-based cell-based primary high throughput screening assay to identify ago...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_AG_FLUO8_1536_1X%ACT PRUN
Name: uHTS identification of small molecule activators of the adaptive arm of the Unfolded ...
Source: Burnham Center for Chemical Genomics
Target: N/A
External Id: BCCG-A405-UPR-XBP1-PrimaryAgonist-Assay
Name: Fluorescence polarization to screen for inhibitor that competite the binding of FadD2...
Source: Broad Institute
Target: FATTY-ACID-CoA LIGASE FADD28 (FATTY-ACID-CoA SYNTHETASE)
External Id: 2147-01_Inhibitor_SinglePoint_HTS_Activity
Name: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfect...
Source: Broad Institute
Target: N/A
External Id: Bursicon-induced LGR2 mediated cAMP production in LGR-2/CRE6x-Luciferase co-transfected HEK293 cells Inhibition - 7011-01_Antagonist_SinglePoint_HTS_Activity
Name: Fluorescence-based cell-based primary high throughput screening assay to identify pos...
Source: The Scripps Research Institute Molecular Screening Center
Target: muscarinic acetylcholine receptor M1 [Homo sapiens]
External Id: CHRM1_PAM_FLUO8_1536_1X%ACT PRUN
Name: Fluorescence polarization-based biochemical high throughput primary assay to identify...
Source: The Scripps Research Institute Molecular Screening Center
Target: RecName: Full=Sialate O-acetylesterase; AltName: Full=H-Lse; AltName: Full=Sialic acid-specific 9-O-acetylesterase; Flags: Precursor [Homo sapiens]
External Id: SIAE_INH_FP_1536_1X%INH PRUN
Name: Absorbance-based primary biochemical high throughput screening assay to identify acti...
Source: The Scripps Research Institute Molecular Screening Center
Target: caspase-3 preproprotein [Homo sapiens]
External Id: PROCASPASE3_ACT_EPIABS_1536_1X%ACT PRUN
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 Synonyms

Phosphinic acid,bis(hydroxyphenylmethyl)
Bis(hydroxyphenylmethyl)phosphinic acid
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