6-Bromo-3-methylindolin-2-one

Modify Date: 2024-01-13 13:37:31

6-Bromo-3-methylindolin-2-one Structure
6-Bromo-3-methylindolin-2-one structure
Common Name 6-Bromo-3-methylindolin-2-one
CAS Number 90725-50-1 Molecular Weight 226.07000
Density 1.535g/cm3 Boiling Point 317.3ºC at 760 mmHg
Molecular Formula C9H8BrNO Melting Point N/A
MSDS N/A Flash Point 145.7ºC

 Names

Name 6-bromo-3-methyl-1,3-dihydroindol-2-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.535g/cm3
Boiling Point 317.3ºC at 760 mmHg
Molecular Formula C9H8BrNO
Molecular Weight 226.07000
Flash Point 145.7ºC
Exact Mass 224.97900
PSA 29.10000
LogP 2.64270
Index of Refraction 1.59

 Synthetic Route

~94%

6-Bromo-3-methylindolin-2-one Structure

6-Bromo-3-methy...

CAS#:90725-50-1

Literature: Bender, David Michael; Forman, Scott Louis; Jones, Winton Dennis; Smith, Daryl Lynn; Zarrinmayeh, Hamideh; Zimmerman, Dennis Michael Patent: US2003/225127 A1, 2003 ; Location in patent: Page 14 ;

~%

6-Bromo-3-methylindolin-2-one Structure

6-Bromo-3-methy...

CAS#:90725-50-1

Literature: Sato Pharmaceutical Co., Ltd.; NAGAI Keita; NAGASAWA Koh; TAKAHASHI Hirobumi; BABA Motoaki; FUJIOKA Shinichi; KONDOH Eri; TANAKA Kenichi; ITOH Yoshiki Patent: EP2669270 A1, 2013 ; Location in patent: Paragraph 0566-0567 ;

~96%

6-Bromo-3-methylindolin-2-one Structure

6-Bromo-3-methy...

CAS#:90725-50-1

Literature: Atwal, Karnail S.; Ferrara, Francis N.; Ding, Charles Z.; Grover, Gary J.; Sleph, Paul G.; Dzwonczyk, Steven; Baird, Anne J.; Normandin, Diane E. Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 304 - 313

~%

6-Bromo-3-methylindolin-2-one Structure

6-Bromo-3-methy...

CAS#:90725-50-1

Literature: AMGEN INC. Patent: WO2009/158011 A1, 2009 ; Location in patent: Page/Page column 34-35 ; WO 2009/158011 A1

~%

6-Bromo-3-methylindolin-2-one Structure

6-Bromo-3-methy...

CAS#:90725-50-1

Literature: Atwal, Karnail S.; Ferrara, Francis N.; Ding, Charles Z.; Grover, Gary J.; Sleph, Paul G.; Dzwonczyk, Steven; Baird, Anne J.; Normandin, Diane E. Journal of Medicinal Chemistry, 1996 , vol. 39, # 1 p. 304 - 313

 Synonyms

6-bromo-3-methyl-1,3-dihydro-2h-indol-2-one
6-bromo-3-methyl-1,3-dihydro-indol-2-one
(3-RS)-6-bromo-2,3-dihydro-3-methyl-1H-indole-2-one
6-Brom-3-methyloxindol
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