α-Helical CRF(9-41)
Modify Date: 2025-08-25 19:02:04
α-Helical CRF(9-41) structure
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Common Name | α-Helical CRF(9-41) | ||
|---|---|---|---|---|
| CAS Number | 90880-23-2 | Molecular Weight | 3826.40 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C166H274N46O53S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of α-Helical CRF(9-41)α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with KB of ~100 nM. α-Helical CRF(9-41) is also a partial agonist of CRF1 receptor with an EC50 of 140 nM[1][2]. |
| Name | α-Helical CRF(9-41) |
|---|
| Description | α-Helical CRF(9-41) is a competitive CRF2 receptor antagonist with KB of ~100 nM. α-Helical CRF(9-41) is also a partial agonist of CRF1 receptor with an EC50 of 140 nM[1][2]. |
|---|---|
| Related Catalog | |
| Target |
KB: ~100 nM (CRF2 receptor)[2] EC50: 140 nM (CRF1 receptor)[2] |
| References |
| Molecular Formula | C166H274N46O53S2 |
|---|---|
| Molecular Weight | 3826.40 |
| InChIKey | PNGVJHODDQMQKT-GVKLFNHCSA-N |
| SMILES | CSCCC(NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C(CCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(Cc1cnc[nH]1)NC(=O)C(Cc1ccccc1)NC(=O)C(NC(=O)C(CC(C)C)NC(=O)C(N)CC(=O)O)C(C)O)C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(N)=O)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(N)=O)C(=O)NC(C)C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(CC(N)=O)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(C)C(N)=O |