H-Gly-Arg-Gly-Asp-Ser-Pro-OH

Modify Date: 2026-07-16 11:57:33

H-Gly-Arg-Gly-Asp-Ser-Pro-OH Structure
H-Gly-Arg-Gly-Asp-Ser-Pro-OH structure
Common Name H-Gly-Arg-Gly-Asp-Ser-Pro-OH
CAS Number 91037-75-1 Molecular Weight 587.58300
Density N/A Boiling Point N/A
Molecular Formula C22H37N9O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of H-Gly-Arg-Gly-Asp-Ser-Pro-OH


GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.

 Names

This table lists Chinese names, IUPAC names and various aliases of this chemical substance.

Name L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl
Synonym More Synonyms

 H-Gly-Arg-Gly-Asp-Ser-Pro-OH Biological Activity

This table contains bioactivity, target information and biological‑assay experimental data of this compound.

Description GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.
Related Catalog
Target

Integrin[1]

In Vitro It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis[1]. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization[2].
References

[1]. Qian J, et al. Transarterial administration of integrin inhibitor loaded nanoparticles combined with transarterial chemoembolization for treating hepatocellular carcinoma in a rat model. World J Gastroenterol. 2016 Jun 7;22(21):5042-9.

[2]. Patel S, et al. Regulation of endothelial cell function by GRGDSP peptide grafted on interpenetrating polymers. J Biomed Mater Res A. 2007 Nov;83(2):423-33.

 Chemical & Physical Properties

This table shows physicochemical parameters including melting point, boiling point, density, solubility and optical rotation. Missing data is marked as N/A.

Molecular Formula C22H37N9O10
Molecular Weight 587.58300
Exact Mass 587.26600
PSA 319.46000
InChIKey NTEDOEBWPRVVSG-UHFFFAOYSA-N
SMILES NCC(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)N1CCCC1C(=O)O
Storage condition 2-8℃

 Synonyms

This table collects all English aliases, systematic names and CAS‑related synonyms of the compound.

H-GLY-ARG-GLY-ASP-SER-PRO-OH

 H-Gly-Arg-Gly-Asp-Ser-Pro-OH | FAQ

This section contains frequently‑asked‑questions about this compound, including basic parameters, properties, storage conditions and corresponding answers.

Q: What is the Chinese name of 91037-75-1?
A: Chinese name of 91037-75-1 is GRGDSP.
Q: What is the molecular formula of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl?
A: Molecular formula of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl is C22H37N9O10.
Q: What is the English name of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl?
A: The English name of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl is L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl.
Q: What English synonyms does L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl have?
A: English synonyms of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl: H-GLY-ARG-GLY-ASP-SER-PRO-OH.
Q: What is the SMILES notation of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl?
A: SMILES notation of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl is NCC(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)N1CCCC1C(=O)O.
Q: What are the storage conditions for L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl?
A: Storage conditions for L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl: 2-8℃.
Q: What is the CAS number of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl?
A: CAS number of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl is 91037-75-1.
Q: What is the molecular weight of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl?
A: Molecular weight of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl is 587.58300.
Q: What are the uses of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl?
A: Main uses of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl: GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.
Q: What is the polar surface area (PSA) of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl?
A: Polar surface area (PSA) of L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl is 319.46000.

 H-Gly-Arg-Gly-Asp-Ser-Pro-OHfactory

This table lists manufacturers and suppliers of this compound, including vendor names and product supply reference information.

Shanghai Nianxing Industrial Co., Ltd
Dayang Chem (Hangzhou) Co., Ltd.
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