H-Gly-Arg-Gly-Asp-Ser-Pro-OH

Modify Date: 2024-01-04 21:31:43

H-Gly-Arg-Gly-Asp-Ser-Pro-OH structure	Common Name	H-Gly-Arg-Gly-Asp-Ser-Pro-OH
	CAS Number	91037-75-1	Molecular Weight	587.58300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₂H₃₇N₉O₁₀	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of H-Gly-Arg-Gly-Asp-Ser-Pro-OH

GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.

Name	L-Proline, glycyl-L-arginylglycyl-L-α-aspartyl-L-seryl
Synonym	More Synonyms

Description	GRGDSP, a synthetic linear RGD peptide, is an integrin inhibitor.
Related Catalog	Signaling Pathways >> Cytoskeleton >> Integrin Research Areas >> Cancer Peptides
Target	Integrin[1]
In Vitro	It is demonstrated that transarterial infusion of GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro integrin-inhibitor which includes RGD-peptide). As a synthetic linear RGD peptide, GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) can inhibit the adherence of tumor cells to endothelial cells of blood vessels and limit its metastasis[1]. GRGDSP (Gly-Arg-Gly-Asp-Ser-Pro) is used as a soluble integrin-blocking RGD-based peptide. GRGDSP is used widely together with other RGD peptides in integrin research. GRGDSP can be used to modify the surface of cardiovascular implants such as vascular grafts to promote endothelialization[2].
References	[1]. Qian J, et al. Transarterial administration of integrin inhibitor loaded nanoparticles combined with transarterial chemoembolization for treating hepatocellular carcinoma in a rat model. World J Gastroenterol. 2016 Jun 7;22(21):5042-9. [2]. Patel S, et al. Regulation of endothelial cell function by GRGDSP peptide grafted on interpenetrating polymers. J Biomed Mater Res A. 2007 Nov;83(2):423-33.

L-Proline, 1-[N-[N-[N-(N2-glycyl-L-arginyl)glycyl]-L-α-aspartyl]-L-seryl]-

H-GLY-ARG-GLY-ASP-SER-PRO-OH

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Price: ￥880/1 mg