8-Epidiosbulbin E acetate

Modify Date: 2024-01-11 14:01:41

8-Epidiosbulbin E acetate Structure
8-Epidiosbulbin E acetate structure
Common Name 8-Epidiosbulbin E acetate
CAS Number 91095-48-6 Molecular Weight 388.42
Density N/A Boiling Point N/A
Molecular Formula C21H24O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 8-Epidiosbulbin E acetate


8-Epidiosbulbin E acetate, a furanoid, is abundant in Dioscorea bulbifera L.. 8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. 8-Epidiosbulbin E acetate induces liver injury in mice[1][2].

 Names

Name 8-Epidiosbulbin E acetate
Synonym More Synonyms

 8-Epidiosbulbin E acetate Biological Activity

Description 8-Epidiosbulbin E acetate, a furanoid, is abundant in Dioscorea bulbifera L.. 8-Epidiosbulbin E acetate exhibits broad-spectrum plasmid-curing activity against multidrug-resistant (MDR) bacteria. 8-Epidiosbulbin E acetate induces liver injury in mice[1][2].
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References

[1]. Shriram V, et al. A potential plasmid-curing agent, 8-epidiosbulbin E acetate, from Dioscorea bulbifera L. against multidrug-resistant bacteria. Int J Antimicrob Agents. 2008 Nov;32(5):405-10.

[2]. Lin D, et al. Role of Metabolic Activation in 8-Epidiosbulbin E Acetate-Induced Liver Injury: Mechanism of Action of the Hepatotoxic Furanoid. Chem Res Toxicol. 2016 Mar 21;29(3):359-66.

 Chemical & Physical Properties

Molecular Formula C21H24O7
Molecular Weight 388.42
Storage condition 2-8℃

 Synonyms

7,10-Methano-2H-pyrano[4,3-g][3]benzoxepin-4,8(1H,4aH)-dione, 6-(acetyloxy)-2-(3-furanyl)octahydro-11b-methyl-, [2S-(2α,4aα,6β,6aα,7α,10α,11aβ,11bα)]- (9CI)
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